Clinical pain is a serious public health issue. Treatment of pain-related suffering requires
knowledge of how pain signals are initially interpreted and subsequently transmitted and …

Neuroimaging and neurophysiological studies have shown that nociceptive stimuli elicit
responses in an extensive cortical network including somatosensory, insular and cingulate …

Pain diagnosis and management would benefit from the development of objective markers
of nociception and pain. Current research addressing this issue has focused on five main …

Pain is a conscious experience, crucial for survival. To investigate the neural basis of pain
perception in humans, a large number of investigators apply noxious stimuli to the body of …

Functional neuroimaging studies in humans have shown that nociceptive stimuli elicit
activity in a wide network of cortical areas commonly labeled as the “pain matrix” and …

Only humans can report feeling pain. In contrast, pain in animals is typically inferred on the
basis of nonverbal behaviour. Unfortunately, these behavioural data can be problematic …

Long perceived as a primitive and poorly differentiated brain structure, the primate insular
cortex recently emerged as a highly evolved, organized and richly connected cortical hub …

Successful behavior requires selection and preferred processing of relevant sensory
information. The cortical representation of relevant sensory information has been related to …

Internally and externally triggered sensory, motor and cognitive events elicit a number of
transient changes in the ongoing electroencephalogram (EEG): event-related brain …

Although laser-evoked electroencephalographic (EEG) responses are increasingly used to
investigate nociceptive pathways, their functional significance remains unclear. The …