Glutathione: a review on biotechnological production

Y Li, G Wei, J Chen - Applied microbiology and biotechnology, 2004 - Springer
Abstract This Mini-Review summarizes the historic developments and technological
achievements in the biotechnological production of glutathione in the past 30 years …

Glutathione production by Saccharomyces cerevisiae: current state and perspectives

LO Santos, PGP Silva, WJF Lemos Junior… - Applied Microbiology …, 2022 - Springer
Abstract Glutathione (L-γ-glutamyl-cysteinyl-glycine, GSH) is a tripeptide synthesized
through consecutive enzymatic reactions. Among its several metabolic functions in cells, the …

Antioxidant defenses of plants and fungi

DA Dalton - Oxidative stress and antioxidant defenses in biology, 1995 - Springer
Plants face a common problem shared by all aerobic organisms. Molecular O 2 is required
to meet the energy demands of metabolism, but the necessary presence of O 2 leads to the …

Bioprocess optimization of glutathione production by Saccharomyces boulardii: biochemical characterization of glutathione peroxidase

H Badr, A El-Baz, I Mohamed, Y Shetaia… - Archives of …, 2021 - Springer
The well-known probiotic GRAS Saccharomyces boulardii (CNCM I-745) was used for the
first time to produce glutathione (GSH). The culture conditions affecting GSH biosynthesis …

Microbial production of glutathione

M Schmacht, E Lorenz, M Senz - World Journal of Microbiology and …, 2017 - Springer
Glutathione (GSH) is a non-coding tripeptide thiol with several important regulative and
protective functions in eukaryotes and in most prokaryotes. The primary function of GSH is to …

The contribution of glutathione to the destabilizing effect of yeast on wheat dough

C Verheyen, A Albrecht, J Herrmann, M Strobl, M Jekle… - Food chemistry, 2015 - Elsevier
Any factor which impairs the development of the gluten network affects the gas retention
capacity and the overall baking performance. This study aimed to examine why rising yeast …

Utilization of amino acids to enhance glutathione production in Saccharomyces cerevisiae

S Wen, T Zhang, T Tan - Enzyme and Microbial Technology, 2004 - Elsevier
The effects of amino acids on glutathione (GSH) production by Saccharomyces cerevisiae
T65 were investigated in this paper. Cysteine was the most important amino acids, which …

Transcriptome analysis reveals the mechanism underlying improved glutathione biosynthesis and secretion in Candida utilis during selenium enrichment

G Zhang, X Yao, C Wang, D Wang, G Wei - Journal of biotechnology, 2019 - Elsevier
The effect of sodium selenite on batch culture of Candida utilis CCTCC M 209298 was
investigated. Cell growth was inhibited while glutathione biosynthesis and secretion were …

Effect of surfactants on extracellular accumulation of glutathione by Saccharomyces cerevisiae

G Wei, Y Li, G Du, J Chen - Process Biochemistry, 2003 - Elsevier
The effects of representative surfactants on the growth of Saccharomyces cerevisiae WSH-
J701 and glutathione (GSH) production were studied. The anionic surfactant sodium …

Improving glutathione production by engineered Pichia pastoris: strain construction and optimal precursor feeding

Y Gao, N Liu, Y Zhu, S Yu, Q Liu, X Shi, J Xu… - Applied Microbiology …, 2022 - Springer
Glutathione (GSH) is a metabolite that plays an important role in the fields of pharmacy, food,
and cosmetics. Thus, it is necessary to increase its production to meet the demands. In this …