Digital detection of exosomes by interferometric imaging
Exosomes, which are membranous nanovesicles, are actively released by cells and have
been attributed to roles in cell-cell communication, cancer metastasis, and early disease …
been attributed to roles in cell-cell communication, cancer metastasis, and early disease …
Protein microarray technology: how far off is routine diagnostics?
The nature of protein microarray platforms is favorable for multiplexing, leading to the
development of tools for personalised medicine and highly precise diagnostics. However, to …
development of tools for personalised medicine and highly precise diagnostics. However, to …
The role of surface chemistry in the efficacy of protein and dna microarrays for label-free detection: An overview
The importance of microarrays in diagnostics and medicine has drastically increased in the
last few years. Nevertheless, the efficiency of a microarray-based assay intrinsically …
last few years. Nevertheless, the efficiency of a microarray-based assay intrinsically …
Development of a high-sensitivity immunoassay for amyloid-beta 1–42 using a silicon microarray platform
In this work, we present a highly sensitive immunoassay for the detection of the Alzheimer's
disease (AD) biomarker amyloid-beta 1–42 (Aβ42) based on a label/label-free microarray …
disease (AD) biomarker amyloid-beta 1–42 (Aβ42) based on a label/label-free microarray …
Single nanoparticle detection for multiplexed protein diagnostics with attomolar sensitivity in serum and unprocessed whole blood
Although biomarkers exist for a range of disease diagnostics, a single low-cost platform
exhibiting the required sensitivity, a large dynamic-range and multiplexing capability, and …
exhibiting the required sensitivity, a large dynamic-range and multiplexing capability, and …
A microwave matrix sensor for multipoint label-free Escherichia coli detection
This paper presents a microwave sensor designed as a capacitive matrix for label-free
Escherichia coli detection. The mean value of capacitances' change in the capacitive matrix …
Escherichia coli detection. The mean value of capacitances' change in the capacitive matrix …
Loss of exosomes in progranulin-associated frontotemporal dementia
L Benussi, M Ciani, E Tonoli, M Morbin, L Palamara… - Neurobiology of …, 2016 - Elsevier
Many cells of the nervous system have been shown to release exosomes, a subclass of
secreted vesicles of endosomal origin capable of transferring biomolecules among cells: this …
secreted vesicles of endosomal origin capable of transferring biomolecules among cells: this …
Modulation of electroosmotic flow in capillary electrophoresis using functional polymer coatings
L Sola, M Chiari - Journal of Chromatography A, 2012 - Elsevier
Capillary electrophoresis (CE) is one of the most powerful techniques for the separation of
biomolecules. However, the separation efficiency of proteins in CE is often compromised by …
biomolecules. However, the separation efficiency of proteins in CE is often compromised by …
Enhancing antibody serodiagnosis using a controlled peptide coimmobilization strategy
Antigen immunoreactivity is often determined by surface regions defined by the 3D
juxtapositions of amino acids stretches that are not continuous in the linear sequence. As …
juxtapositions of amino acids stretches that are not continuous in the linear sequence. As …
A broadband capacitive sensing method for label-free bacterial LPS detection
In this paper, the authors present a new type of highly sensitive label-free microwave sensor
in a form of interdigital capacitor coated with T4 bacteriophage gp37 adhesin. The adhesin …
in a form of interdigital capacitor coated with T4 bacteriophage gp37 adhesin. The adhesin …