Genomic data are ubiquitous across disciplines, from agriculture to biodiversity, ecology,
evolution and human health. However, these datasets often contain noise or errors and are …

Chromosomal structural variation (SV) encompasses a heterogenous class of genetic
variants that exerts strong influences on human health and disease. Despite their …

Abstract Background Circulating tumour DNA (ctDNA) is a subset of cell free DNA (cfDNA)
released by tumour cells into the bloodstream. Circulating tumour DNA has shown great …

Human papilloma virus (HPV) is an etiological factor of head and neck squamous cell
carcinoma (HNSCC). To investigate the role of HPV antigen in anti-tumor immunity, we …

Background Accurate identification of genetic variants, such as point mutations and
insertions/deletions (indels), is crucial for various genetic studies into epidemic tracking …

Genoty**-by-sequencing of reduced-representation libraries has ushered in an era where
genome-wide data can be gotten for any species. Here, I review research on this topic …

Targeted next-generation sequencing (NGS) enables the identification of genomic variants
in cancer patients with high sensitivity at relatively low costs, and has thus opened the era to …

Climate change may result in a drier climate and increased salinization, threatening
agricultural productivity worldwide. Quinoa (Chenopodium quinoa) produces highly …

Background Processing raw genomic data for downstream applications such as imputation,
association studies, and modeling requires numerous third-party bioinformatics software …

High-energy heavy ion beams are a new type of physical mutagen that can produce a wide
range of phenotypic variations. In order to understand the mechanism of high-energy heavy …