The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Serial femtosecond crystallography

TRM Barends, B Stauch, V Cherezov… - Nature reviews Methods …, 2022 - nature.com
With the advent of X-ray free-electron lasers (XFELs), new, high-throughput serial
crystallography techniques for macromolecular structure determination have emerged …

Catalysis and Electron Transfer in De Novo Designed Metalloproteins

KJ Koebke, TBJ Pinter, WC Pitts, VL Pecoraro - Chemical reviews, 2022 - ACS Publications
One of the hallmark advances in our understanding of metalloprotein function is showcased
in our ability to design new, non-native, catalytically active protein scaffolds. This review …

[HTML][HTML] XFELs for structure and dynamics in biology

JCH Spence - IUCrJ, 2017 - scripts.iucr.org
The development and application of the free-electron X-ray laser (XFEL) to structure and
dynamics in biology since its inception in 2009 are reviewed. The research opportunities …

X-ray free-electron lasers for the structure and dynamics of macromolecules

HN Chapman - Annual review of biochemistry, 2019 - annualreviews.org
X-ray free-electron lasers provide femtosecond-duration pulses of hard X-rays with a peak
brightness approximately one billion times greater than is available at synchrotron radiation …

Copper centers in the cryo-EM structure of particulate methane monooxygenase reveal the catalytic machinery of methane oxidation

WH Chang, HH Lin, IK Tsai, SH Huang… - Journal of the …, 2021 - ACS Publications
The particulate methane monooxygenase (pMMO) is the first enzyme in the C1 metabolic
pathway in methanotrophic bacteria. As this enzyme converts methane into methanol …

[PDF][PDF] Sample delivery for serial crystallography at free-electron lasers and synchrotrons

ML Grünbein, G Nass Kovacs - Acta Crystallographica Section D …, 2019 - journals.iucr.org
The high peak brilliance and femtosecond pulse duration of X-ray free-electron lasers
(XFELs) provide new scientific opportunities for experiments in physics, chemistry and …

2′-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography

M Wilamowski, DA Sherrell… - Proceedings of the …, 2021 - National Acad Sciences
The genome of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
coronavirus has a cap** modification at the 5′-untranslated region (UTR) to prevent its …

The pH dependency of N‐converting enzymatic processes, pathways and microbes: effect on net N2O production

JM Blum, Q Su, Y Ma, B Valverde‐Pérez… - Environmental …, 2018 - Wiley Online Library
Nitrous oxide (N2O) is emitted during microbiological nitrogen (N) conversion processes,
when N2O production exceeds N2O consumption. The magnitude of N2O production vs …

Native phasing of x-ray free-electron laser data for a G protein–coupled receptor

A Batyuk, L Galli, A Ishchenko, GW Han, C Gati… - Science …, 2016 - science.org
Serial femtosecond crystallography (SFX) takes advantage of extremely bright and ultrashort
pulses produced by x-ray free-electron lasers (XFELs), allowing for the collection of high …