Metal drugs and the anticancer immune response

B Englinger, C Pirker, P Heffeter, A Terenzi… - Chemical …, 2018 - ACS Publications
The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …

Recent advances in subcellular targeted cancer therapy based on functional materials

WH Chen, GF Luo, XZ Zhang - Advanced Materials, 2019 - Wiley Online Library
Recently, diverse functional materials that take subcellular structures as therapeutic targets
are playing increasingly important roles in cancer therapy. Here, particular emphasis is …

Noble metals in medicine: Latest advances

S Medici, M Peana, VM Nurchi, JI Lachowicz… - Coordination Chemistry …, 2015 - Elsevier
History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …

Silver‐infused porphyrinic metal–organic framework: Surface‐adaptive, on‐demand nanoplatform for synergistic bacteria killing and wound disinfection

Y Zhang, P Sun, L Zhang, Z Wang… - Advanced functional …, 2019 - Wiley Online Library
The fabrication of functional nanoplatforms for combating multidrug‐resistant bacteria is of
vital importance. Among them, silver nanoparticles (Ag NPs) have shown an antibacterial …

Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs

W Liu, R Gust - Coordination Chemistry Reviews, 2016 - Elsevier
The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

Cyclometalated iridium (III) luminescent complexes in therapy and phototherapy

A Zamora, G Vigueras, V Rodríguez… - Coordination Chemistry …, 2018 - Elsevier
Octahedral Ir (III) complexes bearing cyclometalated ligands exhibit a great stability in
biological media and are excellent therapeutical and phototherapeutical candidates for …

Anticancer activity of complexes of the third row transition metals, rhenium, osmium, and iridium

CC Konkankit, SC Marker, KM Knopf, JJ Wilson - Dalton Transactions, 2018 - pubs.rsc.org
The clinical success of the platinum-based chemotherapeutic agents has prompted the
investigation of coordination and organometallic complexes of alternative metal centers for …

Organoiridium complexes: anticancer agents and catalysts

Z Liu, PJ Sadler - Accounts of Chemical Research, 2014 - ACS Publications
Conspectus Iridium is a relatively rare precious heavy metal, only slightly less dense than
osmium. Researchers have long recognized the catalytic properties of square-planar IrI …

Recent development of biotin conjugation in biological imaging, sensing, and target delivery

WX Ren, J Han, S Uhm, YJ Jang, C Kang… - Chemical …, 2015 - pubs.rsc.org
Despite encouraging results from preliminary studies of anticancer therapies, the lack of
tumor specificity remains an important issue in the modern pharmaceutical industry. New …

Recent advances in ruthenium (II) and iridium (III) complexes containing nanosystems for cancer treatment and bioimaging

J Shen, TW Rees, L Ji, H Chao - Coordination chemistry reviews, 2021 - Elsevier
Ruthenium (II) and iridium (III) coordination compounds display excellent structural,
photophysical, and biological properties which make them highly promising as anticancer …