Degeneracy in epilepsy: multiple routes to hyperexcitable brain circuits and their repair

TM Stöber, D Batulin, J Triesch, R Narayanan… - Communications …, 2023 - nature.com
Due to its complex and multifaceted nature, develo** effective treatments for epilepsy is
still a major challenge. To deal with this complexity we introduce the concept of degeneracy …

Recent developments in diagnosis of epilepsy: scope of MicroRNA and technological advancements

R Bandopadhyay, T Singh, MM Ghoneim, S Alshehri… - Biology, 2021 - mdpi.com
Simple Summary Through epilepsy is one of the leading causes of poor mental health,
increased school dropout, and socioeconomic burden, yet the diagnosis remains a …

[HTML][HTML] Relative contributions of different neural sources to the EEG

BJ Thio, WM Grill - Neuroimage, 2023 - Elsevier
Dogma dictates that the EEG signal is generated by postsynaptic currents (PSCs) because
there are an enormous number of synapses in the brain, and PSCs have relatively long …

Combining aperiodic 1/f slopes and brain simulation: An EEG/MEG proxy marker of excitation/inhibition imbalance in Alzheimer's disease

P Martínez‐Cañada, E Perez‐Valero… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Accumulation and interaction of amyloid‐beta (Aβ) and tau proteins during
progression of Alzheimer's disease (AD) are shown to tilt neuronal circuits away from …

[HTML][HTML] Active dendrites and local field potentials: biophysical mechanisms and computational explorations

M Sinha, R Narayanan - Neuroscience, 2022 - Elsevier
Neurons and glial cells are endowed with membranes that express a rich repertoire of ion
channels, transporters, and receptors. The constant flux of ions across the neuronal and glial …

Brain signal predictions from multi-scale networks using a linearized framework

E Hagen, SH Magnusson, TV Ness… - PLOS Computational …, 2022 - journals.plos.org
Simulations of neural activity at different levels of detail are ubiquitous in modern
neurosciences, aiding the interpretation of experimental data and underlying neural …

Spatiotemporal patterns of adaptation-induced slow oscillations in a whole-brain model of slow-wave sleep

C Cakan, C Dimulescu, L Khakimova, D Obst… - Frontiers in …, 2022 - frontiersin.org
During slow-wave sleep, the brain is in a self-organized regime in which slow oscillations
(SOs) between up-and down-states travel across the cortex. While an isolated piece of …

On the validity of electric brain signal predictions based on population firing rates

TV Ness, T Tetzlaff, GT Einevoll, D Dahmen - bioRxiv, 2024 - biorxiv.org
Neural activity at the population level is commonly studied experimentally through
measurements of electric brain signals like local field potentials (LFPs), or …

Increased noise relates to abnormal excitation-inhibition balance in schizophrenia: a combined empirical and computational study

S Abbasi, A Wolff, Y Çatal, G Northoff - Cerebral Cortex, 2023 - academic.oup.com
Electroencephalography studies link sensory processing issues in schizophrenia to
increased noise level—noise here is background spontaneous activity—as measured by the …

[HTML][HTML] Wearable EEG-Based Brain–Computer Interface for Stress Monitoring

B Premchand, L Liang, KS Phua, Z Zhang, C Wang… - NeuroSci, 2024 - mdpi.com
Detecting stress is important for improving human health and potential, because moderate
levels of stress may motivate people towards better performance at cognitive tasks, while …