Nuclear movement within a cell occurs in a variety of eukaryotic organisms including yeasts
and filamentous fungi. Fungal molecular genetic studies identified the minus-end-directed …

Aureobasidium pullulans is a ubiquitous fungus with a wide variety of morphologies and
growth modes including “typical” single-budding yeast, and interestingly, larger …

Positioning the nucleus to a specific cellular location is a prerequisite for high-fidelity
transmission of the genetic material to daughter cells. The cellular location of the nucleus …

Cryptococcus neoformans is a pathogenic yeast that causes lethal cryptococcal meningitis
in immunocompromised patients. One of the challenges in treating cryptococcosis is the …

During chromosome segregation, the spindle assembly checkpoint (SAC) detects errors in
kinetochore-microtubule attachments. Timely activation and maintenance of the SAC until …

Kinetochore clustering, frequently observed in yeasts, plays a key role in genome
organization and chromosome segregation. In the absence of the metaphase plate …

Upon contact with antigen-presenting cells, cytotoxic T lymphocytes (T cells) establish a
highly organized contact zone denoted as the immunological synapse (IS). The formation of …

The nuclear division takes place in the daughter cell in the basidiomycetous budding yeast
Cryptococcus neoformans. Unclustered kinetochores gradually cluster and the nucleus …

During the interphase in mammalian cells, the position of the centrosome is actively
maintained at a small but finite distance away from the nucleus. The perinuclear positioning …

Cryptococcus neoformans is a human fungal pathogen that can cause fatal meningitis in
immunocompromised individuals. Fluconazole (FLC) is a fungistatic drug administered to …