A Compressive Review about Taxol®: History and Future Challenges

J Gallego-Jara, G Lozano-Terol, RA Sola-Martínez… - Molecules, 2020 - mdpi.com
Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …

Recent developments in natural biopolymer based drug delivery systems

T Fazal, BN Murtaza, M Shah, S Iqbal, M Rehman… - RSC …, 2023 - pubs.rsc.org
Targeted delivery of drug molecules to diseased sites is a great challenge in pharmaceutical
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …

Anticancer activity of chitosan, chitosan derivatives, and their mechanism of action

HS Adhikari, PN Yadav - International Journal of Biomaterials, 2018 - Wiley Online Library
Tailoring of chitosan through the involvement of its amino, acetamido, and hydroxy groups
can give derivatives of enhanced solubility and remarkable anticancer activity. The general …

[HTML][HTML] Biomacromolecules as carriers in drug delivery and tissue engineering

Y Zhang, T Sun, C Jiang - Acta Pharmaceutica Sinica B, 2018 - Elsevier
Natural biomacromolecules have attracted increased attention as carriers in biomedicine in
recent years because of their inherent biochemical and biophysical properties including …

Bilirubin nanomedicine rescues intestinal barrier destruction and restores mucosal immunity in colitis

AT Rahman, J Shin, CH Whang, W Jung, D Yoo… - ACS …, 2023 - ACS Publications
Inflammatory bowel disease (IBD) manifests as intestinal barrier destruction, mucosal
immunity dysregulation, and disrupted gut microbiome homeostasis. Conventional anti …

Designing smart polymer conjugates for controlled release of payloads

F Seidi, R Jenjob, D Crespy - Chemical reviews, 2018 - ACS Publications
Incorporating labile bonds inside polymer backbone and side chains yields interesting
polymer materials that are responsive to change of environmental stimuli. Drugs can be …

Insight into divergent chemical modifications of chitosan biopolymer

EM Elnaggar, MS Abusaif, YM Abdel-Baky… - International Journal of …, 2024 - Elsevier
Chitosan is used in many applications due to its biodegradability, biocompatibility,
nontoxicity, nonadhesiveness, and film-forming capabilities. Chitosan has antibacterial and …

Oral delivery of anticancer drugs: challenges and opportunities

K Thanki, RP Gangwal, AT Sangamwar… - Journal of controlled …, 2013 - Elsevier
The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …

Targeted delivery of low molecular drugs using chitosan and its derivatives

JH Park, G Saravanakumar, K Kim, IC Kwon - Advanced drug delivery …, 2010 - Elsevier
Chitosan has prompted the continuous impetus for the development of safe and effective
drug delivery systems because of its unique physicochemical and biological characteristics …

[HTML][HTML] Controlled drug delivery systems for oral cancer treatment—current status and future perspectives

F Ketabat, M Pundir, F Mohabatpour, L Lobanova… - Pharmaceutics, 2019 - mdpi.com
Oral squamous cell carcinoma (OSCC), which encompasses the oral cavity-derived
malignancies, is a devastating disease causing substantial morbidity and mortality in both …