Lipid droplet biogenesis and functions in health and disease
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …
Interplay between lipid metabolism, lipid droplets, and DNA virus infections
MA Farías, B Diethelm-Varela, AJ Navarro, AM Kalergis… - Cells, 2022 - mdpi.com
Lipid droplets (LDs) are cellular organelles rich in neutral lipids such as triglycerides and
cholesterol esters that are coated by a phospholipid monolayer and associated proteins …
cholesterol esters that are coated by a phospholipid monolayer and associated proteins …
Cholesterol esters form supercooled lipid droplets whose nucleation is facilitated by triacylglycerols
C Dumesnil, L Vanharanta, X Prasanna… - Nature …, 2023 - nature.com
Cellular cholesterol can be metabolized to its fatty acid esters, cholesteryl esters (CEs), to be
stored in lipid droplets (LDs). With triacylglycerols (TGs), CEs represent the main neutral …
stored in lipid droplets (LDs). With triacylglycerols (TGs), CEs represent the main neutral …
Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex
Lipid droplets (LDs) are universal lipid storage organelles with a core of neutral lipids, such
as triacylglycerols, surrounded by a phospholipid monolayer. This unique architecture is …
as triacylglycerols, surrounded by a phospholipid monolayer. This unique architecture is …
Triglyceride lipolysis triggers liquid crystalline phases in lipid droplets and alters the LD proteome
Lipid droplets (LDs) are reservoirs for triglycerides (TGs) and sterol-esters (SEs), but how
these lipids are organized within LDs and influence their proteome remain unclear. Using in …
these lipids are organized within LDs and influence their proteome remain unclear. Using in …
Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation
YM Choi, D Ajjaji, KD Fleming, PP Borbat… - Nature …, 2023 - nature.com
Lipid droplets (LDs) are dynamic organelles that contain an oil core mainly composed of
triglycerides (TAG) that is surrounded by a phospholipid monolayer and LD-associated …
triglycerides (TAG) that is surrounded by a phospholipid monolayer and LD-associated …
Seipin accumulates and traps diacylglycerols and triglycerides in its ring-like structure
V Zoni, R Khaddaj, I Lukmantara… - Proceedings of the …, 2021 - National Acad Sciences
Lipid droplets (LDs) are intracellular organelles responsible for lipid storage, and they
emerge from the endoplasmic reticulum (ER) upon the accumulation of neutral lipids, mostly …
emerge from the endoplasmic reticulum (ER) upon the accumulation of neutral lipids, mostly …
[HTML][HTML] Seipin concentrates distinct neutral lipids via interactions with their acyl chain carboxyl esters
Lipid droplets (LDs) are essential for cellular lipid homeostasis by storing diverse neutral
lipids (NLs), such as triacylglycerol (TAG), steryl esters (SE), and retinyl esters (RE). A …
lipids (NLs), such as triacylglycerol (TAG), steryl esters (SE), and retinyl esters (RE). A …
Lipid droplets control mitogenic lipid mediator production in human cancer cells
EJ Jovičić, AP Janež, TO Eichmann, Š Koren… - Molecular …, 2023 - Elsevier
Abstract Objectives Polyunsaturated fatty acids (PUFAs) are structural components of
membrane phospholipids and precursors of oxygenated lipid mediators with diverse …
membrane phospholipids and precursors of oxygenated lipid mediators with diverse …
Production, biosynthesis, and commercial applications of fatty acids from oleaginous fungi
XY Zhang, B Li, BC Huang, FB Wang, YQ Zhang… - Frontiers in …, 2022 - frontiersin.org
Oleaginous fungi (including fungus-like protists) are attractive in lipid production due to their
short growth cycle, large biomass and high yield of lipids. Some typical oleaginous fungi …
short growth cycle, large biomass and high yield of lipids. Some typical oleaginous fungi …