Understanding key mechanisms of exercise-induced cardiac protection to mitigate disease: current knowledge and emerging concepts
The benefits of exercise on the heart are well recognized, and clinical studies have
demonstrated that exercise is an intervention that can improve cardiac function in heart …
demonstrated that exercise is an intervention that can improve cardiac function in heart …
[HTML][HTML] MicroRNAs in heart and circulation during physical exercise
L Wang, Y Lv, G Li, J **ao - Journal of sport and health science, 2018 - Elsevier
Exercise training is beneficial to the cardiovascular system. MicroRNAs (miRNAs, miRs) are
a class of conserved non-coding RNAs and play a wide-ranging role in the regulation of …
a class of conserved non-coding RNAs and play a wide-ranging role in the regulation of …
The role of ceramide accumulation in human induced pluripotent stem cell-derived cardiomyocytes on mitochondrial oxidative stress and mitophagy
M Bekhite, A González-Delgado, S Hübner… - Free Radical Biology …, 2021 - Elsevier
Oversupply of fatty acids (FAs) to cardiomyocytes (CMs) is associated with increased
ceramide content and elevated the risk of lipotoxic cardiomyopathy. Here we investigate the …
ceramide content and elevated the risk of lipotoxic cardiomyopathy. Here we investigate the …
Neuregulin-1/ErbB4 signaling regulates visual cortical plasticity
Experience alters cortical networks through neural plasticity mechanisms. During a
developmental critical period, the most dramatic consequence of occluding vision through …
developmental critical period, the most dramatic consequence of occluding vision through …
Adipose-derived stem cell differentiation as a basic tool for vascularized adipose tissue engineering
AC Volz, B Huber, PJ Kluger - Differentiation, 2016 - Elsevier
The development of in vitro adipose tissue constructs is highly desired to cope with the
increased demand for substitutes to replace damaged soft tissue after high graded burns …
increased demand for substitutes to replace damaged soft tissue after high graded burns …
Brain-derived neurotrophic factor increases vascular endothelial growth factor expression and enhances angiogenesis in human chondrosarcoma cells
Chondrosarcomas are a type of primary malignant bone cancer, with a potent capacity for
local invasion and distant metastasis. Brain-derived neurotrophic factor (BDNF) is commonly …
local invasion and distant metastasis. Brain-derived neurotrophic factor (BDNF) is commonly …
Phosphoinositide 3-kinase: friend and foe in cardiovascular disease
A Ghigo, M Li - Frontiers in pharmacology, 2015 - frontiersin.org
Class I phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases activated by cell
membrane receptors, either receptor tyrosine kinases (RTKs) or G protein–coupled …
membrane receptors, either receptor tyrosine kinases (RTKs) or G protein–coupled …
Generation of human vascularized and chambered cardiac organoids for cardiac disease modelling and drug evaluation
J Yang, W Lei, Y **ao, S Tan, J Yang, Y Lin… - Cell …, 2024 - Wiley Online Library
Human induced pluripotent stem cell (hiPSC)‐derived cardiac organoids (COs) have shown
great potential in modelling human heart development and cardiovascular diseases, a …
great potential in modelling human heart development and cardiovascular diseases, a …
CD133+ cancer stem cells promoted by VEGF accelerate the recurrence of hepatocellular carcinoma
K Liu, M Hao, Y Ouyang, J Zheng, D Chen - Scientific reports, 2017 - nature.com
The role of cancer stem cells (CSCs) in inducing the recurrence of hepatocellular carcinoma
(HCC) after radiofrequency ablation (RFA) remains unclear. Here, we found that a dramatic …
(HCC) after radiofrequency ablation (RFA) remains unclear. Here, we found that a dramatic …
Hypoxia, leptin, and vascular endothelial growth factor stimulate vascular endothelial cell differentiation of human adipose tissue-derived stem cells
MM Bekhite, A Finkensieper, J Rebhan… - Stem cells and …, 2014 - liebertpub.com
The plasticity of human adipose tissue-derived stem cells (hASCs) is promising, but
differentiation in vitro toward endothelial cells is poorly understood. Flow cytometry …
differentiation in vitro toward endothelial cells is poorly understood. Flow cytometry …