Orodispersible films: current innovations and emerging trends

S Jacob, SHS Boddu, R Bhandare, SS Ahmad, AB Nair - Pharmaceutics, 2023 - mdpi.com
Orodispersible films (ODFs) are thin, mechanically strong, and flexible polymeric films that
are designed to dissolve or disintegrate rapidly in the oral cavity for local and/or systemic …

Next-generation pharmaceuticals: the rise of sildenafil citrate ODF for the treatment of men with erectile dysfunction

EA Jannini, SO Vignesh, T Hassan - Therapeutic Delivery, 2025 - Taylor & Francis
Orodispersible film (ODF) is one of the novel formulations that disintegrate rapidly in the
mouth without the requisite for water compared to other conventional oral solid dosage …

Orally dissolving film as a potential vaccine delivery carrier to prevent influenza virus infection

KW Yoon, KB Chu, GD Eom, J Mao, SS Kim, FS Quan - Antiviral Research, 2024 - Elsevier
Orally dissolving films (ODF) are designed to be dissolved on the tongue and absorbed in
the mouth. It offers multiple advantages over the commonly used needle-based vaccines …

How sugar types and fabrication methods affect palatability in paediatric-friendly oromucosal pullulan films of chlorpromazine hydrochloride

K Chachlioutaki, X Li, S Koltsakidis… - Carbohydrate …, 2025 - Elsevier
Ensuring children adhere to their prescribed medication can be challenging, particularly
when a large number of medicines on the market consist of unpalatable drugs and difficult to …

Polyvinyl alcohol-based capsule shells manufactured by injection molding as ready-to-use moisture barriers for the development of delivery systems

M Uboldi, A Gelain, G Buratti, A Chiappa… - International Journal of …, 2024 - Elsevier
In this work, feasibility of injection molding was demonstrated for manufacturing capsule
shells. 600 µm-thick prototypes were successfully molded with pharmaceutical grade low …

Rapid-release and user-friendly costunolide/dehydrocostuslactone hydrophilic nanofibers: Therapeutic effects on acute gastric ulcers

L Li, H Ouyang, J Wu, C Yang, L Wu, X Yuan… - International Journal of …, 2025 - Elsevier
Gastric ulcers often cause postprandial epigastric pain, especially in acute cases. Abnormal
motility, with about 50% of patients having delayed gastric emptying, contributes to ulcer …

Instability and breakup of rayleigh-plateau jets with capillary wave induced by electrowetting-on-dielectric

P Tian, L **a, J Tan, M Zhou, X Yan, D Jiang - Sensors and Actuators B …, 2024 - Elsevier
This paper discusses the lateral disturbances of vertical liquid flow enhancement using
electrowetting-on-dielectric (EWOD) technique, which effectively reducing the breakup …

Evaluation of Modified Guar Gum as Polymer for Electrospun Nanofibrous Film

R Sharma, V Singh, M Ahuja - Polymers for Advanced …, 2025 - Wiley Online Library
This study aimed to fabricate metoclopramide‐loaded nanofibers based on esterified guar
gum using electrospinning. Guar gum was chemically modified through esterification, with …

Improvement of Bioavailability of Sildenafil Citrate Through Taste Masked Orodispersible Film for Pulmonary Hypertension Management

V Mewada, J Shah, S Jacob, H Shah, SHS Boddu… - AAPS …, 2024 - Springer
The oral bioavailability of sildenafil citrate is approximately 43%, primarily limited by the low
aqueous solubility and first-pass effect. Considering the drug properties and …

[HTML][HTML] Effects of Postprandial Factors and Second Meal Intake Time on Bioequivalence Investigation of Tadalafil-Loaded Orodispersible Films in Human Volunteers

SJ Park, MC Gil, BS Lee, M Jung, BJ Lee - Pharmaceutics, 2024 - mdpi.com
Tadalafil (TD) has poor water solubility but is well absorbed without affecting food intake
when administered orally. Owing to patient adherence and therapeutic characteristics, a TD …