Recent advances in iron oxide nanocrystal technology for medical imaging

C Corot, P Robert, JM Idée, M Port - Advanced drug delivery reviews, 2006 - Elsevier
Superparamagnetic iron oxide particles (SPIO and USPIO) have a variety of applications in
molecular and cellular imaging. Most of the recent research has concerned cellular imaging …

Cellular MR imaging

M Modo, M Hoehn, JWM Bulte - Molecular imaging, 2005 - journals.sagepub.com
Cellular MR imaging is a young field that aims to visualize targeted cells in living organisms.
In order to provide a different signal intensity of the targeted cell, they are either labeled with …

Labeling of cells with ferumoxides–protamine sulfate complexes does not inhibit function or differentiation capacity of hematopoietic or mesenchymal stem cells

AS Arbab, GT Yocum, AM Rad… - NMR in Biomedicine …, 2005 - Wiley Online Library
Two FDA‐approved agents, ferumoxides (Feridex®), a suspension of superparamagnetic
iron oxide (SPIO) nanoparticles and protamine sulfate, a drug used to reverse heparin …

Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects

Z Li, Y Suzuki, M Huang, F Cao, X **e, AJ Connolly… - Stem …, 2008 - academic.oup.com
Human embryonic stem (hES) cells are pluripotent stem cells capable of self-renewal and
differentiation into virtually all cell types. Thus, they hold tremendous potential as cell …

Magnetic targeting of human mesenchymal stem cells with internalized superparamagnetic iron oxide nanoparticles

N Landázuri, S Tong, J Suo, G Joseph, D Weiss… - Small, 2013 - Wiley Online Library
Cell therapies offer exciting new opportunities for effectively treating many human diseases.
However, delivery of therapeutic cells by intravenous injection, while convenient, relies on …

Human embryonic stem cell transplantation to repair the infarcted myocardium

J Leor, S Gerecht, S Cohen, L Miller, R Holbova… - Heart, 2007 - heart.bmj.com
Objective: To test the hypothesis that human embryonic stem cells (hESCs) can be guided to
form new myocardium by transplantation into the normal or infarcted heart, and to assess the …

Core-shell magnetoelectric nanorobot–A remotely controlled probe for targeted cell manipulation

S Betal, AK Saha, E Ortega, M Dutta… - Scientific reports, 2018 - nature.com
We have developed a remotely controlled dynamic process of manipulating targeted
biological live cells using fabricated core-shell nanocomposites, which comprises of single …

T1 and T2 relaxivity of intracellular and extracellular USPIO at 1.5 T and 3T clinical MR scanning

GH Simon, J Bauer, O Saborovski, Y Fu, C Corot… - European …, 2006 - Springer
In this study we evaluated the effects of intracellular compartmentalization of the ultrasmall
superparamagnetic iron oxide (USPIO) ferumoxtran-10 on its proton T1 and T2 relaxivities at …

Applications of magnetic nanoparticles in biomedicine

C Bárcena, AK Sra, J Gao - Nanoscale magnetic materials and …, 2009 - Springer
In recent years, magnetic nanoparticles have played an increasing role in biomedical
applications and have been the subject of extensive research investigations. Physical …

Iron particles for noninvasive monitoring of bone marrow stromal cell engraftment into, and isolation of viable engrafted donor cells from, the heart

DJ Stuckey, CA Carr, E Martin‐Rendon, DJ Tyler… - Stem Cells, 2006 - academic.oup.com
Stem cells offer a promising approach to the treatment of myocardial infarction and
prevention of heart failure. We have used iron labeling of bone marrow stromal cells …