Computational models of the basal ganglia: from robots to membranes
With the rapid accumulation of neuroscientific data comes a pressing need to develop
models that can explain the computational processes performed by the basal ganglia …
models that can explain the computational processes performed by the basal ganglia …
Short-term and long-term plasticity at corticostriatal synapses: implications for learning and memory
The striatum is the major division of the basal ganglia, representing the input station of the
circuit and arguably the principal site within the basal ganglia where information processing …
circuit and arguably the principal site within the basal ganglia where information processing …
Opposite influences of endogenous dopamine D1 and D2 receptor activation on activity states and electrophysiological properties of striatal neurons: Studies …
AR West, AA Grace - Journal of Neuroscience, 2002 - jneurosci.org
The tonic influence of dopamine D1 and D2receptors on the activity of striatal neurons in
vivo was investigated by performing intracellular recordings concurrently with reverse …
vivo was investigated by performing intracellular recordings concurrently with reverse …
Cooperative activation of dopamine D1 and D2 receptors increases spike firing of nucleus accumbens neurons via G-protein βγ subunits
FW Hopf, MG Cascini, AS Gordon, I Diamond… - Journal of …, 2003 - jneurosci.org
Dopamine in the nucleus accumbens modulates both motivational and addictive behaviors.
Dopamine D1 and D2 receptors are generally considered to exert opposite effects at the …
Dopamine D1 and D2 receptors are generally considered to exert opposite effects at the …
Relationship between EEG Potentials and Intracellular Activity of Striatal and Cortico-striatal Neurons: an In Vivo Study under Different Anesthetics
S Mahon, JM Deniau, S Charpier - Cerebral Cortex, 2001 - academic.oup.com
The functions of the basal ganglia are achieved through excitation of striatal output neurons
(SONs) by converging cortical glutamergic afferents. We assessed the relationship between …
(SONs) by converging cortical glutamergic afferents. We assessed the relationship between …
Dopamine D2 Receptor Modulation of K+ Channel Activity Regulates Excitability of Nucleus Accumbens Neurons at Different Membrane Potentials
The nucleus accumbens (NAc) is a forebrain area in the mesocorticolimbic dopamine (DA)
system that regulates many aspects of drug addiction. Neuronal activity in the NAc is …
system that regulates many aspects of drug addiction. Neuronal activity in the NAc is …
Brain oscillations, medium spiny neurons, and dopamine
The striatum is part of a multisynaptic loop involved in translating higher order cognitive
activity into action. The main striatal computational unit is the medium spiny neuron, which …
activity into action. The main striatal computational unit is the medium spiny neuron, which …
Anti-Hebbian plasticity drives sequence learning in striatum
Spatio-temporal activity patterns have been observed in a variety of brain areas in
spontaneous activity, prior to or during action, or in response to stimuli. Biological …
spontaneous activity, prior to or during action, or in response to stimuli. Biological …
Electrophysiological interactions between striatal glutamatergic and dopaminergic systems
Glutamatergic and dopaminergic systems play a primary role in frontal‐subcortical circuits
involved in motor and cognitive functions. Considerable evidence has emerged indicating …
involved in motor and cognitive functions. Considerable evidence has emerged indicating …
A dynamical model for the basal ganglia-thalamo-cortical oscillatory activity and its implications in Parkinson's disease
We propose to investigate brain electrophysiological alterations associated with Parkinson's
disease through a novel adaptive dynamical model of the network of the basal ganglia, the …
disease through a novel adaptive dynamical model of the network of the basal ganglia, the …