There is increasing recognition of the importance of blood–brain barrier (BBB) disruption in
aging, dementia, stroke and multiple sclerosis in addition to more commonly-studied …

Objective Summarize evidence for use of advanced MRI techniques as monitoring
biomarkers in the clinic, and highlight the latest bench-to-bedside developments. Methods …

Introduction The ability to ascertain information pertaining to peripheral perfusion through
the analysis of tissues' temporal reaction to the inflow of contrast agent (CA) was first …

Functional magnetic resonance imaging (fMRI) serves as a critical tool for presurgical
map** of eloquent cortex and changes in neurological function in patients diagnosed with …

The blood-brain barrier (BBB) is the interface between the blood and brain tissue, which
regulates the maintenance of homeostasis within the brain. Impaired BBB integrity is …

In the context of neurologic disorders, dynamic susceptibility contrast (DSC) and dynamic
contrast enhanced (DCE) MRI provide valuable insights into cerebral vascular function …

Purpose Software has a substantial impact on quantitative perfusion MRI values. The lack of
generally accepted implementations, code sharing and transparent testing reduces …

Alterations to the cerebral microcirculation have been recognized to play a crucial role in the
development of neurodegenerative disorders. However, the exact role of the microvascular …

BACKGROUND AND PURPOSE: The percentage signal recovery in non-leakage-corrected
(no preload, high flip angle, intermediate TE) DSC-MR imaging is known to differ …

Purpose Despite the excellent capacity of the conventional MRI to image brain tumours,
problems remain in answering a number of critical diagnostic questions. To overcome these …