Immune system dysregulation during spaceflight: potential countermeasures for deep space exploration missions

BE Crucian, A Choukèr, RJ Simpson, S Mehta… - Frontiers in …, 2018 - frontiersin.org
Recent studies have established that dysregulation of the human immune system and the
reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight …

[HTML][HTML] Pectin: A bioactive food polysaccharide with cancer preventive potential

TB Emran, F Islam, S Mitra, S Paul, N Nath, Z Khan… - Molecules, 2022 - mdpi.com
Pectin is an acidic heteropolysaccharide found in the cell walls and the primary and middle
lamella of land plants. To be authorized as a food additive, industrial pectins must meet strict …

Omega-3 polyunsaturated fatty acids for the treatment and prevention of colorectal cancer

AJ Cockbain, GJ Toogood, MA Hull - Gut, 2012 - gut.bmj.com
Omega (ω)-3 polyunsaturated fatty acids (PUFAs) are naturally occurring substances that
are well tolerated and have been used extensively for the prevention of cardiovascular …

Long-term space nutrition: a sco** review

H Tang, HH Rising, M Majji, RD Brown - Nutrients, 2021 - mdpi.com
This sco** review aimed to identify current evidence and gaps in the field of long-term
space nutrition. Specifically, the review targeted critical nutritional needs during long-term …

The role of inflammation in colon cancer

NB Janakiram, CV Rao - Inflammation and cancer, 2014 - Springer
Colorectal cancer (CRC) is the one of the leading causes of cancer-related deaths in the
world. CRC is responsible for more than 600,000 deaths annually and incidence rates are …

Eicosapentaenoic acid reduces rectal polyp number and size in familial adenomatous polyposis

NJ West, SK Clark, RKS Phillips, JM Hutchinson… - Gut, 2010 - gut.bmj.com
Objective The omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) has
anticolorectal cancer activity in vitro and in preclinical models. The present study tested …

Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling …

J Vanamala, L Reddivari, S Radhakrishnan, C Tarver - BMC cancer, 2010 - Springer
Background Obesity is a global phenomenon and is associated with various types of cancer,
including colon cancer. There is a growing interest for safe and effective bioactive …

Diet and supplements and their impact on colorectal cancer

M Pericleous, D Mandair… - Journal of gastrointestinal …, 2013 - pmc.ncbi.nlm.nih.gov
Background Colorectal cancer is the third commonest cancer and the third leading cause of
cancer death among men and women. It has been proposed that dietary factors are …

Recent progress and treatment strategy of pectin polysaccharide based tissue engineering scaffolds in cancer therapy, wound healing and cartilage regeneration

J Koshy, D Sangeetha - International Journal of Biological Macromolecules, 2024 - Elsevier
Natural polymers and its mixtures in the form of films, sponges and hydrogels are playing a
major role in tissue engineering and regenerative medicine. Hydrogels have been …

Polypotency of the immunomodulatory effect of pectins

SV Popov, YS Ovodov - Biochemistry (Moscow), 2013 - Springer
Pectins are the major component of plant cell walls, and they display diverse biological
activities including immunomodulation. The pectin macromolecule contains fragments of …