How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …

Synapses are intercellular junctions specialized for fast, point-to-point information transfer
from a presynaptic neuron to a postsynaptic cell. At a synapse, a presynaptic terminal …

Modern recording techniques enable large-scale measurements of neural activity in a
variety of model organisms. The dynamics of neural activity shed light on how organisms …

Dendrite morphology is necessary for the correct integration of inputs that neurons receive.
The branching mechanisms allowing neurons to acquire their type-specific morphology …

Leukocyte cell-derived chemotaxin-2 (LECT2, also named ChM-II), initially identified as a
chemokine mediating neutrophil migration, is a multifunctional secreted factor involved in …

Stringent targeting of membrane proteins to corresponding organelles is essential for
organelle identity and functions. In addition to molecular pathways that target proteins to …

Proper morphogenesis of dendrites plays a fundamental role in the establishment of neural
circuits. The molecular mechanism by which dendrites grow highly complex branches is not …

Cell-cell interactions shape cellular function and ultimately organismal phenotype.
Interacting cells can sense their mutual distance using combinations of ligand-receptor …

Transcription factors (TFs) play critical roles in specifying many aspects of neuronal cell fate
including dendritic morphology. How TFs are accurately regulated during neuronal …

Endoplasmic reticulum (ER) is characterized by interconnected tubules and sheets.
Neuronal ER adopts specific morphology in axons, dendrites and soma. Here we study …