Morpholine, a six-membered heterocycle containing one nitrogen and one oxygen atom, is a
moiety of great significance. It forms an important intermediate in many industrial and …

Currently, the development of anticancer drug resistance is significantly restricted the clinical
efficacy of the most commonly prescribed anticancer drug. Malignant disease is widely …

A new class of benzimidazole-based derivatives (4a–j, 5, and 6) with potential dual
inhibition of EGFR and BRAFV600E has been developed. The newly synthesized …

The discovery of potent STAT3 inhibitors has gained noteworthy impetus in the last decade.
In line with this trend, considering the proven biological importance of 1, 2, 4-triazoles …

Acetylation, a key component in post-translational modification regulated by HATs and
HDACs, is relevant to many crucial cellular contexts in organisms. Based on crucial …

Abstract A series of imidazo [2, 1-b] thiazoles bearing pyrazole moieties 4–6 (a–c) was
synthesized through the reaction of 6-hydrazinylimidazo [2, 1-b] thiazoles 3a–c with different …

This review brings forth the potential of thiazole derivatives for their anticancer activities. The
emphasis is placed on the structural diversity of thiazole derivatives, responsible for their …

Fused heterobicyclic systems have gained much importance in the field of medicinal
chemistry because of their broad spectrum of physiological activities. Among the …

ABSTRACT A series of new selenocyanates and diselenides bearing interesting bioactive
scaffolds (quinoline, quinoxaline, acridine, chromene, furane, isosazole, etc.) was …

Recently we described some (thiazol-2-yl) hydrazones as antiprotozoal, antifungal and anti-
MAO agents as well as Gcn5 HAT inhibitors. Among these last compounds, CPTH2 and …