Hepatocellular carcinoma (HCC) is the leading cause of cancer-related death. The
accumulation of genetic and epigenetic changes is closely related to the occurrence and …

Clustered regularly interspaced short palindromic repeats‐associated protein
(CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust …

Background/Aims: Osteonecrosis of the femoral head (ONFH) is a devastating orthopedic
disease. Previous studies suggested that stromal-cell-derived factor (SDF)-1 was involved in …

Abstract Glypican-3 (GPC-3) is predominantly found in the placenta and fetal liver, with
limited expression in adult tissues. Its re-expression in hepatocellular carcinoma (HCC) and …

Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide and
has a poor prognosis. Although immune checkpoint inhibitors have entered a new era of …

Hepatitis is an inflammatory liver disease primarily caused by hepatitis A (HAV), B (HBV), C
(HCV), D (HDV), and E (HEV) viruses. The chronic forms of hepatitis resulting from HBV and …

Primary liver cancer is one of the leading causes of cancer-related deaths worldwide. China
has more than 55% liver cancer cases globally. The development of hepatocellular …

Metastasis is the main cause of death in cancer patients; there is currently no effective
treatment for cancer metastasis. This is primarily due to our insufficient understanding of the …

Background Chemoresistance is one of the leading causes that severely limits the success
of osteosarcoma treatment. Evaluating chemoresistance before chemotherapy poses a new …

Liver diseases are one of the leading causes of mortality in the world, mainly caused by
different etiological agents, alcohol consumption, viruses, drug intoxication, and malnutrition …