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Recent advances in bioactive pyrazoles
Pyrazole is a five membered and two-nitrogen containing heterocyclic ring. These structures
have been investigated in the development of novel compounds with hypoglycemic …
have been investigated in the development of novel compounds with hypoglycemic …
The synthetic and biological attributes of pyrazole derivatives: A review
Pyrazole nucleus is a unique structural scaffold which acts as an interesting template for
combinatorial as well as medicinal chemistry. This review presents a detailed overview on …
combinatorial as well as medicinal chemistry. This review presents a detailed overview on …
[HTML][HTML] Synthesis and anticonvulsant activity of some 2-pyrazolines derived from chalcones
Abstract Synthesis of chalcones (1, 3-diarylprop-2-en-1-ones) and 2-pyrazoline derivatives
has been an active field of research due to their established pharmacological effects. In this …
has been an active field of research due to their established pharmacological effects. In this …
Novel [l,2,4]triazolo[3,4-a]isoquinoline chalcones as new chemotherapeutic agents: Block IAP tyrosine kinase domain and induce both intrinsic and extrinsic …
Two novel chemotherapeutic chalcones were synthesized and their structures were
confirmed by different spectral tools. Theoretical studies such as molecular modeling were …
confirmed by different spectral tools. Theoretical studies such as molecular modeling were …
A new insight into the synthesis and biological activities of pyrazole based derivatives
This review aims to collate literature work reported by researchers (from 1994 to 2021) to
provide an overview of the available methodologies for the synthesis and diverse …
provide an overview of the available methodologies for the synthesis and diverse …
Anticancer Activity of New Bis-(3-(Thiophen-2-yl)-1H-Pyrazol-4-yl)Chalcones: Synthesis, in-Silico, and in-Vitro Studies
A series of bis-chalcones with alkyl linkers incorporating 3-(thiophen-2-yl) pyrazole 5–10
has been prepared by the condensation reaction of two moles of 3-(thiophen-2-yl) pyrazole …
has been prepared by the condensation reaction of two moles of 3-(thiophen-2-yl) pyrazole …
Design, synthesis and anticancer activities evaluation of novel 5H-dibenzo [b, e] azepine-6, 11-dione derivatives containing 1, 3, 4-oxadiazole units
X He, X Li, J Liang, C Cao, S Li, T Zhang… - Bioorganic & medicinal …, 2018 - Elsevier
Rucaparib and PJ34 were used as the structural model for the design of novel 5 H-dibenzo
[b, e] azepine-6, 11-dione derivatives containing 1, 3, 4-oxadiazole units. And target …
[b, e] azepine-6, 11-dione derivatives containing 1, 3, 4-oxadiazole units. And target …
an overview of recent developments in coordination chemistry of polypyrazolylmethylamines. Complexes with N-scorpionate ligands created in situ from pyrazole …
A Adach - Journal of Coordination Chemistry, 2017 - Taylor & Francis
This paper reviews the coordination chemistry of polypyrazolylmethylamines as tripodal
tetradentate (LS= N, N, N-tris (3, 5-dimethylpyrazol-1-ylmethyl) amine) and dipodal tridentate …
tetradentate (LS= N, N, N-tris (3, 5-dimethylpyrazol-1-ylmethyl) amine) and dipodal tridentate …
Methyl-linked pyrazoles: synthetic and medicinal perspective
Pyrazoles, an important and well-known class of the azole family, have been found to show
a large number of applications in various fields, especially medicinal chemistry. Pyrazole …
a large number of applications in various fields, especially medicinal chemistry. Pyrazole …
[PDF][PDF] Synthesis, characterization and antibacterial evaluation of some azole derivatives
Purpose: Tremendous rise in development of resistance to the antimicrobials has created
alarming situation for researchers and clinicians. Method: In this regard, an attempt has …
alarming situation for researchers and clinicians. Method: In this regard, an attempt has …