Systematic reviews seek to identify all research that meets the eligibility criteria. However,
this goal can be compromised by 'non‐reporting bias'. The convincing evidence for the …

Bone morphogenetic protein-2 (BMP-2) is currently the only Food and Drug Administration
(FDA)-approved osteoinductive growth factor used as a bone graft substitute. However, with …

Fractures are the most common large-organ, traumatic injuries to humans. The repair of
bone fractures is a postnatal regenerative process that recapitulates many of the ontological …

Bone morphogenetic proteins (BMPs) are responsible for bone formation during
embryogenesis and bone regeneration and remodeling. The osteoinductive action of BMPs …

Background context Recombinant human bone morphogenetic protein 2 (rhBMP-2) is a very
potent osteogenic growth factor that has been used successfully in various spine fusions …

The balance between bone forming cells (osteoblasts/osteocytes) and bone resorbing cells
(osteoclasts) plays a crucial role in tissue homeostasis and bone repair. Several hormones …

The incidence of rheumatic diseases such as rheumatoid arthritis and osteoarthritis and
injuries to articular cartilage that lead to osteochondral defects is predicted to rise as a result …

In response to mechanical forces and the aging process, bone in the adult skeleton is
continuously remodeled by a process in which old and damaged bone is removed by bone …

Biological systems have evolved to utilize numerous proteins with capacity to bind
polysaccharides for the purpose of optimizing their function. A well-known subset of these …

BMPs are members of the transforming growth factor-β (TGF-β) superfamily and have been
extensively studied due to their excellent osteoinductive ability and multiple functions …