Reducing oxidative stress stands at the center of a prevention and control strategy for
mitigating cellular senescence and aging. Kidney disease is characterized by a premature …

Ethnopharmacological relevance Liquiritin is a flavonoid derived from Radix et Rhizoma
Glycyrrhizae, which is a widely used traditional Chinese medicine with the effects of …

Coronary artery disease (CAD) is the leading cause of death worldwide. Oxidative stress
and inflammation are major mechanisms responsible for the progression of CAD. Nuclear …

Osteoarthritis (OA) is one of the most prevalent musculoskeletal disorders globally, and
treating OA remains a significant challenge. Currently, pharmacological treatments primarily …

Cerebral ischemic stroke (IS) is still a difficult problem to be solved; energy metabolism
failure is one of the main factors causing mitochondrion dysfunction and oxidation stress …

Oxidative stress is a major component of cell damage and cell fat, and as such, it occupies a
central position in the pathogenesis of metabolic disease. Nuclear factor-erythroid-derived 2 …

Vitamin D deficiency has been linked to several major chronic diseases, such as
cardiovascular and neurodegenerative diseases, diabetes, and cancer, linked to oxidative …

Ischemia-reperfusion myocardial damage is a paradoxical tissue injury occurring during
percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI) patients …

The pathophysiology of muscle damage in peripheral artery disease (PAD) includes
increased oxidant production and impaired antioxidant defenses. Epicatechin (EPI), a …

Objectives Diabetic nephropathy (DN) is the most common microvascular complication of
diabetes mellitus. This study investigated the mechanism of triptolide (TP) in podocyte injury …