The fibrinolytic system is activated concurrently with coagulation; it regulates haemostasis
and prevents thrombosis by restricting clot formation to the area of vascular injury and …

The liver plays a crucial role in all aspects of coagulation, because most of the factors that
regulate procoagulation, anticoagulation, and fibrinolysis are produced and/or cleared by …

Background The coagulation status of dogs with liver disease is difficult to predict using
conventional coagulation testing. Hypothesis/Objectives To evaluate thromboelastography …

Background: Hemorrhagic shock and volume replacement can alter coagulation. Synthetic
colloids, hydroxyethyl starch (HES), and gelatin, may enhance hypocoagulability. Our …

Objective—To determine minimum plasma concentrations of the antifibrinolytic agents
tranexamic acid (TEA) and ϵ-aminocaproic acid (EACA) needed to completely inhibit …

OBJECTIVE To assess pharmacokinetics of tranexamic acid (TXA) in dogs and assess
antifibrinolytic properties of TXA in canine blood by use of a thromboelastography-based in …

Insulinomas are the most common neoplasms of the endocrine pancreas in dogs, leading to
persistent hypoglycemia due to inappropriate insulin secretion. The standard treatment is …

Background No treatment other than platelet administration is known to protect against
spontaneous hemorrhage in thrombocytopenic dogs. Objectives Primary: determine if …

Hyperfibrinolysis (HFL) is a pathophysiological mechanism that has not been described in
dogs or cats extensively. The aim of this study was to describe rotational thromboelastometry …

OBJECTIVES To identify short‐term wound complications and associated predictive factors
following amputation in dogs and cats. MATERIALS AND METHODS Retrospective review …