Antibodies in neurological diseases: Established, emerging, explorative

LY Li, A Keles, MA Homeyer, H Prüss - Immunological reviews, 2024 - Wiley Online Library
Within a few years, autoantibodies targeting the nervous system resulted in a novel disease
classification. For several of them, which we termed 'established', direct pathogenicity has …

Autoantibodies as diagnostic and prognostic cancer biomarker: Detection techniques and approaches

S Yadav, N Kashaninejad, MK Masud… - Biosensors and …, 2019 - Elsevier
Autoantibodies produced by the patients' own immune systems in response to foreign
substances are emerging as an attractive biomarker for early detection of cancer. These …

Autoantibody profiles in patients with immune checkpoint inhibitor-induced neurological immune related adverse events

L Müller-Jensen, S Knauss, L Ginesta Roque… - Frontiers in …, 2023 - frontiersin.org
Background Neurological immune-related adverse events (irAE-n) are severe and
potentially fatal toxicities of immune checkpoint inhibitors (ICI). To date, the clinical …

Cognitive impact of neuronal antibodies: encephalitis and beyond

LL Gibson, A McKeever, E Coutinho, C Finke… - Translational …, 2020 - nature.com
Cognitive dysfunction is a common feature of autoimmune encephalitis. Pathogenic
neuronal surface antibodies are thought to mediate distinct profiles of cognitive impairment …

Serum anti-NMDA receptor antibodies are linked to memory impairment 12 months after stroke

FA Arlt, PS Sperber, R von Rennenberg, P Gebert… - Molecular …, 2024 - nature.com
Patients suffering from strokes are at increased risk of develo** post-stroke dementia.
Serum anti-NMDA receptor autoantibodies (NMDAR1-abs) have been associated with …

[HTML][HTML] Neuronal autoantibodies associated with cognitive impairment in melanoma patients

F Bartels, T Strönisch, K Farmer, K Rentzsch… - Annals of …, 2019 - Elsevier
Background Cancer-related cognitive impairment is an important complication in cancer
patients, yet the underlying mechanisms remain unknown. Over the last decade, the field of …

Association between neuronal autoantibodies and cognitive impairment in patients with lung cancer

F Bartels, MM Wandrey, A Aigner, T Strönisch… - JAMA …, 2021 - jamanetwork.com
Importance Paraneoplastic neurological syndromes are associated with neuronal
autoantibodies, and some of these autoantibodies are associated with neuropsychological …

Autoantibodies against N-methyl-d-aspartate receptor 1 in health and disease

H Ehrenreich - Current opinion in neurology, 2018 - journals.lww.com
The present knowledge on the (patho) physiological role of NMDAR1-AB is very limited and
still characterized by adamant rumors. Much more experimental work and more solid and …

[HTML][HTML] Depressive symptoms and anti-N-methyl-D-aspartate-receptor GluN1 antibody seropositivity in the PROSpective cohort with incident stroke

PS Sperber, P Gebert, LHA Broersen, A Kufner… - Brain, Behavior, & …, 2023 - Elsevier
Abstract Background Anti-NMDA-receptor GluN1 antibodies (NMDAR1-abs) are present in
an autoimmune encephalitis with severe neuropsychiatric symptoms. We aimed to estimate …

Clinical, cognitive and neuroanatomical associations of serum NMDAR autoantibodies in people at clinical high risk for psychosis

TA Pollak, MJ Kempton, C Iyegbe, A Vincent… - Molecular …, 2021 - nature.com
Serum neuronal autoantibodies, such as those to the NMDA receptor (NMDAR), are
detectable in a subgroup of patients with psychotic disorders. It is not known if they are …