Sequencing-based analyses of microbiomes have traditionally focused on addressing the
question of community membership and profiling taxonomic abundance through amplicon …

Antibiotic resistance is a natural feature of diverse microbial ecosystems. Although recent
studies of the antibiotic resistome have highlighted barriers to the horizontal transfer of …

The human gut microbiome harbors hundreds of bacterial species with diverse biochemical
capabilities. Dozens of drugs have been shown to be metabolized by single isolates from …

In soil ecosystems, microorganisms produce diverse secondary metabolites such as
antibiotics, antifungals and siderophores that mediate communication, competition and …

Soil plays a crucial role in ecosystem functioning. In the 1990s ecosystem services (ES)
research focused on develo** the concept and framework and only a few studies linked …

The wellbeing of soils is crucial for securing food production worldwide. The soil health (SH)
concept has been introduced due to an evolving understanding that soil is not just a growing …

As environmental DNA (eDNA) studies have grown in popularity for use in ecological
applications, it has become clear that their results differ in significant ways from those of …

Enzymes are versatile catalysts and their synthetic potential has been recognized for a long
time. In order to exploit their full potential, enzymes often need to be re-engineered or …

High-throughput DNA sequencing has proven invaluable for investigating diverse
environmental and host-associated microbial communities. In this Review, we discuss …

BACKGROUND: Nature has been a source of medicinal products for millennia, with many
useful drugs developed from plant sources. Following discovery of the penicillins, drug …