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APT‐weighted MRI: techniques, current neuro applications, and challenging issues
Amide proton transfer‐weighted (APTw) imaging is a molecular MRI technique that
generates image contrast based predominantly on the amide protons in mobile cellular …
generates image contrast based predominantly on the amide protons in mobile cellular …
[HTML][HTML] Chemical exchange saturation transfer magnetic resonance imaging and its main and potential applications in pre-clinical and clinical studies
W Dou, CYE Lin, H Ding, Y Shen, C Dou… - … imaging in medicine …, 2019 - ncbi.nlm.nih.gov
Chemical exchange saturation transfer (CEST) imaging is a novel contrast mechanism,
relying on the exchange between mobile protons in amide (-NH), amine (-NH 2) and …
relying on the exchange between mobile protons in amide (-NH), amine (-NH 2) and …
Predicting IDH mutation status in grade II gliomas using amide proton transfer‐weighted (APTw) MRI
Purpose To assess the amide proton transfer‐weighted (APTw) MRI features of isocitrate
dehydrogenase (IDH)‐wildtype and IDH‐mutant grade II gliomas and to test the hypothesis …
dehydrogenase (IDH)‐wildtype and IDH‐mutant grade II gliomas and to test the hypothesis …
Quantitative assessment of amide proton transfer (APT) and nuclear overhauser enhancement (NOE) imaging with extrapolated semisolid magnetization transfer …
Purpose To evaluate the use of three extrapolated semisolid magnetization transfer
reference (EMR) methods to quantify amide proton transfer (APT) and nuclear Overhauser …
reference (EMR) methods to quantify amide proton transfer (APT) and nuclear Overhauser …
[HTML][HTML] Amide proton transfer-weighted magnetic resonance image-guided stereotactic biopsy in patients with newly diagnosed gliomas
Abstract Purpose Pathological assessment using World Health Organization (WHO) criteria
is the gold standard for diagnosis of gliomas. However, the accuracy of diagnosis is limited …
is the gold standard for diagnosis of gliomas. However, the accuracy of diagnosis is limited …
Molecular MRI differentiation between primary central nervous system lymphomas and high-grade gliomas using endogenous protein-based amide proton transfer …
Objectives To show the ability of using the amide proton transfer-weighted (APTW) MRI
signals as imaging biomarkers to differentiate primary central nervous system lymphomas …
signals as imaging biomarkers to differentiate primary central nervous system lymphomas …
Investigation of the contribution of total creatine to the CEST Z‐spectrum of brain using a knockout mouse model
The current study aims to assign and estimate the total creatine (tCr) signal contribution to
the Z‐spectrum in mouse brain at 11.7 T. Creatine (Cr), phosphocreatine (PCr) and protein …
the Z‐spectrum in mouse brain at 11.7 T. Creatine (Cr), phosphocreatine (PCr) and protein …
Chemical exchange saturation transfer imaging of creatine, phosphocreatine, and protein arginine residue in tissues
Chemical exchange saturation transfer (CEST) MRI has become a promising technique to
assay target proteins and metabolites through their exchangeable protons, noninvasively …
assay target proteins and metabolites through their exchangeable protons, noninvasively …
Quantifying amide proton exchange rate and concentration in chemical exchange saturation transfer imaging of the human brain
Current chemical exchange saturation transfer (CEST) neuroimaging protocols typically
acquire CEST-weighted images, and, as such, do not essentially provide quantitative proton …
acquire CEST-weighted images, and, as such, do not essentially provide quantitative proton …
Evaluation of the molecular origin of amide proton transfer–weighted imaging
Purpose To evaluate the assumption in amide proton transfer weighted (APTw) imaging that
the APT dominates over the relayed nuclear Overhauser enhancement (rNOE) and other …
the APT dominates over the relayed nuclear Overhauser enhancement (rNOE) and other …