L‐type Ca2+ channels in heart and brain
J Striessnig, A **gera, G Kaur… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
L‐type calcium channels (Cav1) represent one of the three major classes (Cav1–3) of
voltage‐gated calcium channels. They were identified as the target of clinically used calcium …
voltage‐gated calcium channels. They were identified as the target of clinically used calcium …
Calmodulin regulation (calmodulation) of voltage-gated calcium channels
Calmodulin regulation (calmodulation) of the family of voltage-gated CaV1-2 channels
comprises a prominent prototype for ion channel regulation, remarkable for its powerful …
comprises a prominent prototype for ion channel regulation, remarkable for its powerful …
Voltage-gated calcium channels: key players in sensory coding in the retina and the inner ear
Calcium influx through voltage-gated Ca (CaV) channels is the first step in synaptic
transmission. This review concerns CaV channels at ribbon synapses in primary sense …
transmission. This review concerns CaV channels at ribbon synapses in primary sense …
Calcium sensors in neuronal function and dysfunction
Calcium signaling in neurons as in other cell types can lead to varied changes in cellular
function. Neuronal Ca2+ signaling processes have also become adapted to modulate the …
function. Neuronal Ca2+ signaling processes have also become adapted to modulate the …
A mutation in CABP2, expressed in cochlear hair cells, causes autosomal-recessive hearing impairment
I Schrauwen, S Helfmann, A Inagaki, F Predoehl… - The American Journal of …, 2012 - cell.com
CaBPs are a family of Ca 2+-binding proteins related to calmodulin and are localized in the
brain and sensory organs, including the retina and cochlea. Although their physiological …
brain and sensory organs, including the retina and cochlea. Although their physiological …
Lead poisoning: acute exposure of the heart to lead ions promotes changes in cardiac function and Cav1. 2 ion channels
G Ferreira de Mattos, C Costa, F Savio, M Alonso… - Biophysical …, 2017 - Springer
Abstract Lead ions (Pb 2+) possess characteristics similar to Ca 2+. Because of this and its
redox capabilities, lead causes different toxic effects. The neurotoxic effects have been well …
redox capabilities, lead causes different toxic effects. The neurotoxic effects have been well …
Ca2+-dependent modulation of voltage-gated Ca2+ channels
C Christel, A Lee - Biochimica et Biophysica Acta (BBA)-General Subjects, 2012 - Elsevier
BACKGROUND: Voltage-gated (Cav) Ca2+ channels are multi-subunit complexes that play
diverse roles in a wide variety of tissues. A fundamental mechanism controlling Cav channel …
diverse roles in a wide variety of tissues. A fundamental mechanism controlling Cav channel …
Progress in the structural understanding of voltage-gated calcium channel (CaV) function and modulation
Voltage-gated calcium channels (CaVs) are large, transmembrane multiprotein complexes
that couple membrane depolarization to cellular calcium entry. These channels are central …
that couple membrane depolarization to cellular calcium entry. These channels are central …
CaBP1 and 2 enable sustained CaV1. 3 calcium currents and synaptic transmission in inner hair cells
To encode continuous sound stimuli, the inner hair cell (IHC) ribbon synapses utilize
calcium-binding proteins (CaBPs), which reduce the inactivation of their Ca V 1.3 calcium …
calcium-binding proteins (CaBPs), which reduce the inactivation of their Ca V 1.3 calcium …
L-Type Ca2+ Channel Regulation by Calmodulin and CaBP1
JB Ames - Biomolecules, 2021 - mdpi.com
L-type voltage-gated Ca2+ channels (CaV1. 2 and CaV1. 3, called CaV) interact with the
Ca2+ sensor proteins, calmodulin (CaM) and Ca2+ binding Protein 1 (CaBP1), that …
Ca2+ sensor proteins, calmodulin (CaM) and Ca2+ binding Protein 1 (CaBP1), that …