A review of toxicity mechanism studies of electronic cigarettes on respiratory system

L Wang, Y Wang, J Chen, P Liu, M Li - International Journal of Molecular …, 2022 - mdpi.com
Electronic cigarettes (e-cigarettes) have attracted much attention as a new substitute for
conventional cigarettes. E-cigarettes are first exposed to the respiratory system after …

E-cigarette va** associated acute lung injury (EVALI): state of science and future research needs

A Marrocco, D Singh, DC Christiani… - Critical reviews in …, 2022 - Taylor & Francis
Abstract “E-Cigarette (e-cig) Va**-Associated Acute Lung Injury”(EVALI) has been linked
to vitamin-E-acetate (VEA) and Δ-9-tetrahydrocannabinol (THC), due to their presence in …

Caveolin-1 knockout mitigates breast cancer metastasis to the lungs via integrin α3 dysregulation in 4T1-induced syngeneic breast cancer model

DP Singh, R Pathak, N Chintalaramulu, A Pandit… - Cancer Gene …, 2024 - nature.com
Abstract Caveolin-1 (Cav-1) is a critical lipid raft protein playing dual roles as both a tumor
suppressor and promoter. While its role in tumorigenesis, progression, and metastasis has …

Rafting on the evidence for lipid raft-like domains as hubs triggering environmental toxicants' cellular effects

D Marques-da-Silva, R Lagoa - Molecules, 2023 - mdpi.com
The plasma membrane lipid rafts are cholesterol-and sphingolipid-enriched domains that
allow regularly distributed, sub-micro-sized structures englobing proteins to …

Interplay between proteasome function and inflammatory responses in e-cig vapor condensate-challenged lung epithelial cells

R Begum, S Thota, S Batra - Archives of Toxicology, 2023 - Springer
Exposure to cigarettes and other nicotine-based products results in persistent inflammation
in the lung. In recent years, electronic cigarettes (e-cigs) have become extremely popular …

Regulatory roles of Osteopontin in lung epithelial inflammation and epithelial‐telocyte interaction

H Fu, X Liu, L Shi, L Wang, H Fang… - Clinical and …, 2023 - Wiley Online Library
Background Lung epithelial cells play important roles in lung inflammation and injury,
although mechanisms remain unclear. Osteopontin (OPN) has essential roles in epithelial …

Estimation of health risks caused by metals contained in e-cigarette aerosol through passive va**

WC Su, J Lee, K Zhang, SW Wong, A Buu - Toxics, 2023 - mdpi.com
It is expected that secondary exposure to e-cigarette aerosol (passive va**) will soon
become an issue of public health. Passive va** inhales e-cigarette aerosol containing …

[HTML][HTML] Effect of e-cigarette aerosol on gingival mucosa structure and proinflammatory cytokine response

H Alanazi, M Rouabhia - Toxicology Reports, 2022 - Elsevier
We evaluated the effect of multiple exposures to electronic cigarettes on human oral mucosa
structure and proinflammatory cytokine secretion. A 3D air-liquid interface human gingival …

Ferroptosis‐associated cholesterol metabolism regulated by p85α in human bronchial epithelial cells with smoking

L Li, X Wang - Clinical and Translational Discovery, 2022 - Wiley Online Library
Background Chronic obstructive pulmonary disease (COPD) is characterized by
inflammation, airflow obstruction, and lung damage resulting from multiple causes, in …

Flavoured and nicotine-containing e-liquids impair homeostatic properties of an alveolar-capillary cell model

AN Sabo, E Filaudeau, S Da Silva, G Becker… - Food and Chemical …, 2023 - Elsevier
Most people consider that electronic cigarettes are safer than tobacco and are marketed as
quit-smoking products. The e-liquid, which usually contains propylene glycol (PG) and …