Diseases are a significant impediment to aquaculture's sustainable and healthy growth. The
aquaculture industry is suffering significant financial losses as a result of the worsening …

In the past decades, global freshwater fish production has been rapidly growing, while
cyprinid takes the largest portion. Along with the rapid rise of novel forms of intensive …

Trained immunity is a long-term memory of innate immune cells, generating an improved
response upon reinfection. Shigella is an important human pathogen and inflammatory …

In fish, DNA vaccines have been shown to give very high protection in experimental facilities
against a number of viral diseases, particularly diseases caused by rhabdoviruses …

Zebrafish possess a highly developed immune system that is remarkably similar to the
human one. Therefore, it is expected that the majority of the signalling pathways and …

Fish Red-Blood Cells (RBCs) are nucleated cells that can modulate the expression of
different sets of genes in response to stimuli, playing an active role in the homeostasis of the …

Background: Some fish viruses, such as piscine orthoreovirus and infectious salmon anemia
virus, target red blood cells (RBCs), replicate inside them and induce an immune response …

Trained immunity (TRAIM) may be defined as a form of memory where innate immune cells
such as monocytes, macrophages, dendritic and natural killer (NK) cells undergo an …

TNFα is a pleiotropic pro-inflammatory cytokine with a key role in the activation of the
immune system to fight viral infections. Despite its antiviral role, a few viruses might utilize …

To investigate fish innate immunity, we have conducted organ and cell immune-related
transcriptomic as well as immunohistologic analysis in mutant zebra fish (Danio rerio) …