Stem and progenitor cells have been observed to contribute to regenerative processes in
acute renal failure and chronic kidney disease. Recent research has delved into the intricate …

Idiopathic membranous nephropathy (IMN) is a glomerular disease that is prevalent in
elderly males. The pathogenesis of IMN includes abnormal autoimmunity and complement …

Diabetic kidney disease (DKD) is the most common cause of kidney failure, characterized by
chronic inflammation and fibrosis. The complement system is increasingly implicated in the …

Abstract Background Complement 3 glomerulopathy (C3G) and immune complex
membranoproliferative glomerulonephritis (IC-MPGN) are ultra-rare chronic kidney diseases …

The complement system plays a crucial role in regulating the inflammatory responses in
kidney transplantation, potentially contributing to early decline in kidney function. Ischemia …

The complement system includes soluble and cell surface proteins and is an important arm
of the innate immune system. Once activated, the complement system rapidly generates …

Introduction Kidney diseases pose a serious healthcare problem because of their high
prevalence, worsening of patients' quality of life, and high mortality. Patients with kidney …

Diabetic kidney disease (DKD) is a serious microvascular complication of type 2 diabetes
mellitus (T2DM). Despite the numerous genetic loci that have been associated with the …

The increasing availability of clinically approved genetic tests for kidney disease has
spurred the growth in the use of these tests in kidney transplant practice. Neither the testing …

In glomerulopathies, endothelial dysfunction and the presence of histological vascular
lesions such as thrombotic microangiopathy, arteriolar hyalinosis, and arteriosclerosis are …