SARS-CoV-2 infects cells via its spike protein binding to its surface receptor on target cells
and results in acute symptoms involving especially the lungs known as COVID-19. However …

The current pandemic caused by the COVID-19 disease has reached everywhere in the
world and has affected every aspect of our lives. As of the current data, the World Health …

Parallel cascade selection molecular dynamics-based ligand binding-path sampling (LB-
PaCS-MD) was combined with fragment molecular orbital (FMO) calculations to reveal the …

Despite the fast development of vaccines, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is still circulating and generating variants of concern (VoC) that escape the …

In this paper, an environmentally benign, convenient, and efficient one-pot three-component
reaction has been developed for the regioselective synthesis of novel 5-aroyl (or …

Plant-based flavonoids have been evaluated as inhibitors of β-coronavirus replication and
as therapies for COVID-19 on the basis of their safety profile and widespread availability …

Covid-19 variants transmissibility was quantitatively analyzed in silico to understand the
reaction mechanisms and to find the reaction inhibitors. Especially, SARS-CoV-2 omicron …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a serious
global public health threat. The evolving strains of SARS-CoV-2 have reduced the …

The emergence of the COVID-19 situation has become a global issue due to the lack of
effective antiviral drugs for treatment. Flavonoids are a class of plant secondary metabolites …

Traditional Chinese medicine (TCM) has been extensively employed for the treatment of
coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome …