Current opinion on risk assessment of cosmetics

KB Kim, SJ Kwack, JY Lee, S Kacew… - Journal of Toxicology …, 2021 - Taylor & Francis
Risk assessment of cosmetic ingredients is a useful scientific method to characterize
potential adverse effects resulting from using cosmetics. The process of risk assessment …

A review of phthalate pharmacokinetics in human and rat: what factors drive phthalate distribution and partitioning?

E Domínguez-Romero, M Scheringer - Drug metabolism reviews, 2019 - Taylor & Francis
Phthalates are a class of compounds that have been extensively used as plasticizers in
different applications. Several phthalates have been recognized as substances of very high …

Toxicological Study of Human Exposure to Mixtures of Chemicals: Challenges and Approaches

M Nian, G Braun, BI Escher, M Fang - Environmental Science & …, 2024 - ACS Publications
Humans are exposed to highly diverse mixtures of complex and often unknown
compositions, which may adversely impact their health. There is a lack of guidance on how …

[HTML][HTML] An integrated exposure and pharmacokinetic modeling framework for assessing population-scale risks of phthalates and their substitutes

Y Wu, Z Song, JC Little, M Zhong, H Li, Y Xu - Environment International, 2021 - Elsevier
To effectively incorporate in vitro-in silico-based methods into the regulation of consumer
product safety, a quantitative connection between product phthalate concentrations and in …

Prenatal exposure to PFOS and PFOA in a pregnant women cohort of Catalonia, Spain

J Rovira, MÁ Martínez, RP Sharma, T Espuis… - Environmental …, 2019 - Elsevier
This study was aimed at assessing the prenatal exposure to perfluorooctane sulfonic acid
(PFOS) and perfluorooctanoic acid (PFOA) in a cohort of pregnant women living in Reus …

Modeling di (2-ethylhexyl) phthalate (DEHP) and its metabolism in a body's organs and tissues through different intake pathways into human body

A Li, L Kang, R Li, S Wu, K Liu, X Wang - International Journal of …, 2022 - mdpi.com
Phthalate esters (PAEs) are ubiquitous in indoor environments as plasticizers in indoor
products. Residences are often exposed to indoor PAEs in the form of gas, particles, settled …

Inflammatory cytokines as key players of apoptosis induced by environmental estrogens in the ovary

FL Zhang, L Kong, AH Zhao, W Ge, ZH Yan, L Li… - Environmental …, 2021 - Elsevier
Natural and synthetic environmental estrogens (EEs), interfering with the physiological
functions of the body's estrogens, are widespread and are rising much concern for their …

Hepatotoxicity of the pesticides imazalil, thiacloprid and clothianidin–individual and mixture effects in a 28-day study in female Wistar rats

J Alarcan, J Waizenegger, MLM Solano… - Food and Chemical …, 2020 - Elsevier
Humans are exposed to pesticide residues through various food products. As these residues
can occur in mixtures, there is a need to investigate possible mixture effects on human …

Physiologically-based toxicokinetic modeling of human dermal exposure to diethyl phthalate: Application to health risk assessment

M Hu, Y Zhang, M Zhan, G He, W Qu, Y Zhou - Chemosphere, 2022 - Elsevier
Diethyl phthalate (DEP) has been most frequently detected in personal care products
(PCPs) as a solvent followed by indoor air as one of the semi-volatile organic compounds …

Phthalates and alternative plasticizers differentially affect phenotypic parameters in gonadal somatic and germ cell lines

A Rajkumar, T Luu, MA Beal… - Biology of …, 2022 - academic.oup.com
The developmental and reproductive toxicity associated with exposure to phthalates has
motivated a search for alternatives. However, there is limited knowledge regarding the …