Aneurysmal subarachnoid hemorrhage

S D'Souza - Journal of neurosurgical anesthesiology, 2015 - journals.lww.com
Aneurysmal subarachnoid hemorrhage (SAH) is a worldwide health burden with high fatality
and permanent disability rates. The overall prognosis depends on the volume of the initial …

An overview of management of intracranial hypertension in the intensive care unit

T Schizodimos, V Soulountsi, C Iasonidou… - Journal of …, 2020 - Springer
Intracranial hypertension (IH) is a clinical condition commonly encountered in the intensive
care unit, which requires immediate treatment. The maintenance of normal intracranial …

Hypertonic saline versus other intracranial pressure–lowering agents for people with acute traumatic brain injury

H Chen, Z Song, JA Dennis - Cochrane Database of …, 2019 - cochranelibrary.com
Background Increased intracranial pressure has been shown to be strongly associated with
poor neurological outcomes and mortality for patients with acute traumatic brain injury …

The role of the microcirculation in delayed cerebral ischemia and chronic degenerative changes after subarachnoid hemorrhage

L Østergaard, R Aamand… - Journal of Cerebral …, 2013 - journals.sagepub.com
The mortality after aneurysmal subarachnoid hemorrhage (SAH) is 50%, and most survivors
suffer severe functional and cognitive deficits. Half of SAH patients deteriorate 5 to 14 days …

Hypertonic saline or mannitol for treating elevated intracranial pressure in traumatic brain injury: a meta-analysis of randomized controlled trials

J Gu, H Huang, Y Huang, H Sun, H Xu - Neurosurgical review, 2019 - Springer
Hyperosmolar therapy is regarded as the mainstay for treatment of elevated intracranial
pressure (ICP) in traumatic brain injury (TBI). This still has been disputed as application of …

Hypertonic saline reduces cumulative and daily intracranial pressure burdens after severe traumatic brain injury

HS Mangat, YL Chiu, LM Gerber, M Alimi… - Journal of …, 2015 - thejns.org
OBJECT Increased intracranial pressure (ICP) in patients with traumatic brain injury (TBI) is
associated with a higher mortality rate and poor outcome. Mannitol and hypertonic saline …

Hypertonic saline is superior to mannitol for the combined effect on intracranial pressure and cerebral perfusion pressure burdens in patients with severe traumatic …

HS Mangat, X Wu, LM Gerber, JT Schwarz… - …, 2020 - journals.lww.com
BACKGROUND Hypertonic saline (HTS) and mannitol are effective in reducing intracranial
pressure (ICP) after severe traumatic brain injury (TBI). However, their simultaneous effect …

A systematic review of randomized controlled trials comparing hypertonic sodium solutions and mannitol for traumatic brain injury: implications for emergency …

S Burgess, RB Abu-Laban, RS Slavik… - Annals of …, 2016 - journals.sagepub.com
Objective: To comparatively evaluate hypertonic sodium (HTS) and mannitol in patients
following acute traumatic brain injury (TBI) on the outcomes of all-cause mortality …

Topiramate is more effective than acetazolamide at lowering intracranial pressure

WJ Scotton, HF Botfield, CSJ Westgate… - …, 2019 - journals.sagepub.com
Background The management of idiopathic intracranial hypertension focuses on reducing
intracranial pressure to preserve vision and reduce headaches. There is sparse evidence to …

Traumatic brain injury

K Hackenberg, A Unterberg - Der Nervenarzt, 2016 - Springer
Unter jungen Erwachsenen gilt das Schädel-Hirn-Trauma (SHT) als die häufigste Ursache
von langfristiger Behinderung und Tod, wodurch das SHT eine enorme gesundheitliche und …