Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …

Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …

Abstract Background Circulating tumor cells (CTCs) hold immense promise in guiding
treatment strategies for advanced gastric cancer (GC). However, their clinical impact has …

Histopathological examination (biopsy) is the “gold standard” for the diagnosis of colorectal
cancer (CRC). However, biopsy is an invasive method, and due to the temporal and spatial …

Intermediate filaments (IFs) formed by vimentin are less understood than their cytoskeletal
partners, microtubules and F‐actin, but the unique physical properties of IFs, especially their …

Aim A programmed death 1 (PD-1) inhibitor coupled with radiotherapy and antiangiogenic
therapy is a potential therapeutic strategy for advanced hepatocellular carcinoma (HCC). We …

The prognostic value of SII (Systemic Immune-Inflammation Index) in HER-2-positive breast
cancer (BC) patients, regardless of whether they receive trastuzumab treatment, and its …

Gastrointestinal (GI) cancers account for 35% of cancer-related deaths, predominantly due
to their ability to spread and generate drug-tolerant metastases. Arising from different …

Circulating tumor cells (CTCs) as a liquid biopsy have great potential in clinical applications
and basic cancer research, but their clinical use in gastric cancer remains unclear. This …