Medical digital twins, which are potentially vital for personalized medicine, have become a
recent focus in medical research. Here we present an overview of the state of the art in …

The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Myocardial infarction (MI) remains a leading cause of morbidity and mortality. In
atherothrombotic MI (ST-elevation MI and type 1 non-ST-elevation MI), coronary artery …

Precision medicine is the vision of health care where therapy is tailored to each patient. As
part of this vision, digital twinning technology promises to deliver a digital representation of …

Catheter ablation is nowadays considered the treatment of choice for numerous cardiac
arrhythmias in different clinical scenarios. Fluoroscopy has traditionally been the primary …

Purpose of review Contemporary ablation for complex arrhythmias raises several
challenges for electroanatomic map**. We examine how current and emerging systems …

Microvascular injury immediately following reperfusion therapy in acute myocardial
infarction (MI) has emerged as a driving force behind major adverse cardiovascular events …

Aims Epicardial adipose tissue might promote atrial fibrillation (AF) in several ways,
including infiltrating the underlying atrial myocardium. However, the role of this potential …

Sudden cardiac death is often caused by ventricular arrhythmias driven by reentry.
Comprehensive characterization of the potential triggers and substrate in survivors of …

Background Among patients with ischemic cardiomyopathy (ICM) and nonischemic
cardiomyopathy (NICM), myocardial fibrosis is associated with an increased risk for …