Adipose tissue is an immunologically active organ that controls host physiology, partly
through the release of mediators termed adipokines. In obesity, adipocytes and infiltrating …

Obesity and related metabolic syndromes have been recognized as important disease risks,
in which the role of adipokines cannot be ignored. Adiponectin (ADP) is one of the key …

Obesity is one of the most prevalent and increasing metabolic disorders and is considered
one of the twelve risk factors for dementia. Numerous studies have demonstrated that …

Mitochondria is a subcellular organelle involved in the pathogenesis of cellular stress,
immune responses, differentiation, metabolic disorders, aging, and death by regulating …

Adiponectin (APN) is an adipokine which predominantly expresses in adipocytes with
neuroprotective and anti-inflammatory effects. We have recently indicated that circulatory …

Background Aging of the brain is a major contributor to the onset and progression of
neurodegenerative diseases. Conventional treatments for these diseases are often limited …

The incidence of aging-related neurodegenerative disorders and neurocritical care diseases
is increasing worldwide. Microglia, the main inflammatory cells in the brain, could be …

Dementia is a detrimental neuropathologic condition with considerable physical, mental,
social, and financial impact on patients and society. Patients with metabolic syndrome …

Central neurological disorders are significant contributors to morbidity, mortality, and long-
term disability globally in modern society. These encompass neurodegenerative diseases …

Although many efforts have been made to understand the pathophysiological mechanisms
of COVID-19, critical gaps remain to be explored. This study aimed to investigate potential …