Since the introduction of the central dogma of molecular biology in 1958, various RNA
species have been discovered. Messenger RNAs transmit genetic instructions from DNA to …

MicroRNAs (miRNAs) are a group of small non‐coding RNAs that are involved in regulating
a range of developmental and physiological processes; their dysregulation has been …

Obsessive–compulsive disorder (OCD) is characterized by repetitive thoughts and
behaviours that are experienced as unwanted. Family and twin studies have demonstrated …

We present a DNA library preparation method that has allowed us to reconstruct a high-
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …

Disease is often the result of an aberrant or inadequate response to physiologic and
pathophysiologic stress. Studies over the last 10 years have uncovered a recurring …

Malignant neoplasms are consistently among the top four leading causes of death in all age
groups in the United States, despite a concerted effort toward develo** novel therapeutic …

MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

MicroRNAs (miRNAs) are endogenous∼ 23 nt RNAs that play important gene-regulatory
roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their …

MicroRNA (miRNA) alterations are involved in the initiation and progression of human
cancer. The causes of the widespread differential expression of miRNA genes in malignant …

Many studies have highlighted the role that microRNAs have in physiological processes and
how their deregulation can lead to cancer. More recently, it has been proposed that the …