DNA replication in eukaryotic cells initiates from large numbers of sites called replication
origins. Initiation of replication from these origins must be tightly controlled to ensure the …

Errors occurring during DNA replication can result in inaccurate replication, incomplete
replication, or re-replication, resulting in genome instability that can lead to diseases such as …

Stress granules are mRNA-protein granules that form when translation initiation is limited,
and they are related to pathological granules in various neurodegenerative diseases. Super …

The proliferative activity of tumour cells represents an important prognostic marker in the
diagnosis of cancer. One of the methods for assessing the proliferative activity of cells is the …

The accurate and complete replication of genomic DNA is essential for all life. In eukaryotic
cells, the assembly of the multi-enzyme replisomes that perform replication is divided into …

Plants have evolved a unique system in which the plant hormone auxin directly induces
rapid degradation of the AUX/IAA family of transcription repressors by a specific form of the …

Hypoxia is a physiological cue that impacts diverse physiological processes, including
energy metabolism, autophagy, cell motility, angiogenesis, and erythropoiesis. One of the …

Aberrant DNA replication is a major source of the mutations and chromosome
rearrangements that are associated with pathological disorders. When replication is …

▪ Abstract The maintenance of the eukaryotic genome requires precisely coordinated
replication of the entire genome each time a cell divides. To achieve this coordination …

Helicases and translocases are a ubiquitous, highly diverse group of proteins that perform
an extraordinary variety of functions in cells. Consequently, this review sets out to define a …