Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection
Immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is
central to long-term control of the current pandemic. Despite our rapidly advancing …
central to long-term control of the current pandemic. Despite our rapidly advancing …
Antibody-mediated neutralization of SARS-CoV-2
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …
[HTML][HTML] Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination
During the SARS-CoV-2 pandemic, novel and traditional vaccine strategies have been
deployed globally. We investigated whether antibodies stimulated by mRNA vaccination …
deployed globally. We investigated whether antibodies stimulated by mRNA vaccination …
New-onset IgG autoantibodies in hospitalized patients with COVID-19
COVID-19 is associated with a wide range of clinical manifestations, including autoimmune
features and autoantibody production. Here we develop three protein arrays to measure IgG …
features and autoantibody production. Here we develop three protein arrays to measure IgG …
Delayed production of neutralizing antibodies correlates with fatal COVID-19
Recent studies have provided insights into innate and adaptive immune dynamics in
coronavirus disease 2019 (COVID-19). However, the exact features of antibody responses …
coronavirus disease 2019 (COVID-19). However, the exact features of antibody responses …
[HTML][HTML] Maturation and persistence of the anti-SARS-CoV-2 memory B cell response
Memory B cells play a fundamental role in host defenses against viruses, but to date, their
role has been relatively unsettled in the context of SARS-CoV-2. We report here a …
role has been relatively unsettled in the context of SARS-CoV-2. We report here a …
Understanding neutralising antibodies against SARS-CoV-2 and their implications in clinical practice
NYL Pang, ASR Pang, VT Chow, DY Wang - Military Medical Research, 2021 - Springer
SARS-CoV-2 is a newly identified member of the coronavirus family that has caused the
Coronavirus disease 2019 (COVID-19) pandemic. This rapidly evolving and unrelenting …
Coronavirus disease 2019 (COVID-19) pandemic. This rapidly evolving and unrelenting …
The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind, placebo …
Background Ivermectin inhibits the replication of SARS-CoV-2 in vitro at concentrations not
readily achievable with currently approved doses. There is limited evidence to support its …
readily achievable with currently approved doses. There is limited evidence to support its …
Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity?
Many nations are pursuing the rollout of SARS-CoV-2 vaccines as an exit strategy from
unprecedented COVID-19-related restrictions. However, the success of this strategy relies …
unprecedented COVID-19-related restrictions. However, the success of this strategy relies …
Immunity to SARS‐CoV‐2 induced by infection or vaccination
Adaptive immune responses play critical roles in viral clearance and protection against re‐
infection, and SARS‐CoV‐2 is no exception. What is exceptional is the rapid …
infection, and SARS‐CoV‐2 is no exception. What is exceptional is the rapid …