Following a strong regain of interest over the past 20 years in the chemistry of allenes, this
“forgotten” family of unsaturated molecules is undergoing a renaissance. In this context, the …

The allene functionality has participated in one of the most exciting voyages in organic
chemistry, from chemical curiosities to a recurring building block in modern organic …

More than 50 years have passed since Haszeldine reported the first addition of a
trifluoromethyl radical to an allene; in the intervening years, both the chemistry of allenes …

Abstract Synergistic Pd/Cu catalysis has been utilized in the Sonogashira reaction since
1975. However, this strategy has not received much attention from the organic chemist …

A copper-catalyzed regiodivergent hydrosilylation of a wide range of simple allenes is
reported. Linear and branched allylsilanes were formed by judicious choice of solvents …

The development of general catalytic methods for the regio-and stereoselective construction
of phosphoryl derivatives from identical substrates remains a formidable challenge in …

Propargylic alcohols are readily available bifunctional (alkyne and hydroxyl groups)
synthons, which recognize as one of the attractive synthetic feedstock in organic …

Enantioselective synthesis of fully substituted allenes has been a challenge due to the non-
rigid nature of the axial chirality, which spreads over three carbon atoms. Here we show the …

Cleavage of C–O and C–N bonds mediated by transition metals is a promising
bioorthogonal approach to rescue the activity of caged molecules, such as proteins and …

The copper-catalyzed reaction of allenes with bis (pinacolato) diboron and acyl electrophiles
is reported. In this transformation, acyl fluorides have been proven to be more efficient …