Synthesis of some new nanoparticles mixed metal complexes of febuxostat in presence of 2, 2′-bipyridine: Characterization, DFT, antioxidant and molecular docking …

LM Abbass, SA Sadeek, MAER Aziz, WA Zordok… - Journal of Molecular …, 2023 - Elsevier
Abstract New Mn (II), Fe (III), Co (II), and Ni (II) complexes with urate lowing drug febuxostat
(FEB) and 2, 2′-bipyridine (Bipy) were designed and depicted. Elemental analysis, molar …

A novel electrochemical sensor based on gold nanoparticles decorated functionalized carbon nanofibers for selective determination of xanthine oxidase inhibitor …

H Ibrahim, Y Temerk - Sensors and Actuators B: Chemical, 2021 - Elsevier
Febuxostat is an antihyperuricemic drug used for the treatment of hyperuricemia in patients
with chronic gout. Hence, in this work, there was an impetus to construct a sensitive …

Allopurinol loaded transferosomes for the alleviation of symptomatic after-effects of Gout: An Account of Pharmaceutical implications

R Tiwari, G Tiwari, R Singh - Current Drug Therapy, 2020 - ingentaconnect.com
Background: The present study assessed the transdermal potential of transferosomes
loaded with allopurinol for the treatment of gout. Methods: Transferosomes of allopurinol …

Innovative HPTLC method with fluorescence detection for assessment of febuxostat–montelukast combination and study of their protective effects against gouty …

NM Hosny, NN Atia, SM El-Gizawy, DM Badary… - Analyst, 2018 - pubs.rsc.org
The present study was designed to evaluate the potential protective effects of the cysteinyl
leukotriene receptor blocker montelukast (MNK) and the xanthine oxidase inhibitor …

HPTLC and spectrophotometric estimation of febuxostat and diclofenac potassium in their combined tablets

FA El-Yazbi, OA Amin, EI El-Kimary… - Journal of …, 2016 - academic.oup.com
An accurate, precise, rapid, specific and economic high-performance thin-layer
chromatographic (HPTLC) method has been developed for the simultaneous quantitative …

Innovative thin-layer chromatographic method combined with fluorescence detection for specific determination of Febuxostat: Application in biological fluids

AMI Mohamed, MA Omar, SM Derayea, MA Hammad… - Talanta, 2018 - Elsevier
A newly developed thin-layer chromatographic (TLC) method coupled with fluorescence
detection for specific determination of Febuxostat (FEB) was designed. The proposed …

Bioequivalance and pharmacokinetic study of febuxostat in human plasma by using LC-MS/MS with liquid liquid extraction method

BR Chandu, K Kanala, NT Hwisa, P Katakam… - Springerplus, 2013 - Springer
A bioequivalence study was proved of generic Febuxostat 80 mg tablets (T) in healthy
volunteers. For this purpose, Authors developed a simple, sensitive, selective, rapid, rugged …

[PDF][PDF] Development of Validated Stability Indicating HPTLC Method for Estimation of Febuxostat in Bulk and Tablet Dosage Form by Using QBD Approach

V Kharate, M Kuchekar, M Harde, B Pimple… - International Journal of …, 2023 - academia.edu
Objective: Development of a simple, reliable, time-tested, stability-focused HPTLC method
for determining febuxostat (FEB) in bulk and pharmaceutical formulation. Methods …

Facile micelle-enhanced spectrofluorimetric method for picogram level determination of febuxostat; application in tablets and in real human plasma

NN Atia, SM El-Gizawy, NM Hosny - Microchemical Journal, 2019 - Elsevier
Ultrasensitive, specific, rapid and economic spectrofluorimetric method was developed and
validated for determination of a selective xanthine oxidase inhibitor; Febuxostat (FBX) in …

Development and validation of a stability-indicating RP-HPLC method for the determination of febuxostat (a xanthine oxidase inhibitor)

MA Mukthinuthalapati, SPK Bandaru… - Journal of …, 2013 - academic.oup.com
Febuxostat is a selective inhibitor of xanthine oxidase that is used for the treatment of
hyperuricaemia in patients with gout. An isocratic liquid chromatographic method was …