Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …

The purpose of this paper is to provide an integrative review and offer novel insights
regarding human research with classic psychedelics (classic hallucinogens), which are …

Psychedelic drugs are making waves as modern trials support their therapeutic potential
and various media continue to pique public interest. In this opinion piece, we draw attention …

Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …

Research into the basic effects and therapeutic applications of psychedelic drugs has grown
considerably in recent years. Yet, pressing questions remain regarding the substances' …

Responses to psychedelics are notoriously difficult to predict, yet significant work is currently
underway to assess their therapeutic potential and the level of interest in psychedelics …

Psilocybin is a classic psychedelic compound that may have efficacy for the treatment of
mood and substance use disorders. Acute psilocybin effects include reduced negative …

The posterior cingulate cortex is a highly connected and metabolically active brain region.
Recent studies suggest it has an important cognitive role, although there is no consensus …