[HTML][HTML] Hypoxia, partial EMT and collective migration: Emerging culprits in metastasis

K Saxena, MK Jolly, K Balamurugan - Translational oncology, 2020 - Elsevier
Epithelial-mesenchymal transition (EMT) is a cellular biological process involved in
migration of primary cancer cells to secondary sites facilitating metastasis. Besides, EMT …

Molecular mechanisms of anti-estrogen therapy resistance and novel targeted therapies

R Ozyurt, B Ozpolat - Cancers, 2022 - mdpi.com
Simple Summary Estrogen receptor-positive (ER+) breast cancer is a notable cause of
global death from breast cancer in premenopausal and postmenopausal women. Lethality is …

Molecular epigenetic dynamics in breast carcinogenesis

A Hazra, P Bose, P Sunita, SP Pattanayak - Archives of Pharmacal …, 2021 - Springer
Breast cancer has become one of the most common dreadful diseases that target women
across the globe. The most obvious reasons we associate with it are either genetic …

Nanoparticle-based antioxidants in stress signaling and programmed cell death in breast cancer treatment

Y Herdiana, S Sriwidodo, FF Sofian, G Wilar, A Diantini - Molecules, 2023 - mdpi.com
Breast cancer (BC) is a complex and heterogeneous disease, and oxidative stress is a
hallmark of BC. Oxidative stress is characterized by an imbalance between the production of …

DNA methylation profile of inflammatory breast cancer and its impact on prognosis and outcome

FLC Faldoni, D Bizinelli, CP Souza, IVV Santana… - Clinical …, 2024 - Springer
Background Inflammatory breast cancer (IBC) is a rare disease characterized by rapid
progression, early metastasis, and a high mortality rate. Methods Genome-wide DNA …

[HTML][HTML] Correlation analysis of lymphocyte-monocyte ratio with pathological complete response and clinical prognosis of neoadjuvant chemotherapy in patients with …

X Meng, X Wang, C Jiang, S Zhang, S Cheng - Translational Oncology, 2022 - Elsevier
Purpose Inflammation plays an important role in tumor proliferation, metastasis, and
chemotherapy resistance. Peripheral blood lymphocyte-monocyte ratio (LMR) has been …

Novel forms of prostate cancer chemoresistance to successful androgen deprivation therapy demand new approaches: Rationale for targeting BET proteins

JO Mori, JS Shafran, M Stojanova, MH Katz… - The …, 2022 - Wiley Online Library
In patients with prostate cancer, the duration of remission after treatment with androgen
deprivation therapies (ADTs) varies dramatically. Clinical experience has demonstrated …

Potential effects of nutrition-based weight loss therapies in reversing obesity-related breast cancer epigenetic marks

PM Lorenzo, AB Crujeiras - Food & Function, 2021 - pubs.rsc.org
Obesity is a modifiable risk factor of breast cancer and epigenetic marks were proposed as a
relevant mechanistic link. These mechanisms can be remodelled by modifying lifestyle …

Metadherin Regulates Inflammatory Breast Cancer Invasion and Metastasis

G Ortiz-Soto, NS Babilonia-Díaz… - International Journal of …, 2023 - mdpi.com
Inflammatory breast cancer (IBC) is one of the most lethal subtypes of breast cancer (BC),
accounting for approximately 1–5% of all cases of BC. Challenges in IBC include accurate …

Advances of epigenetic biomarkers and epigenome editing for early diagnosis in breast cancer

P Sarvari, P Sarvari, I Ramírez-Díaz… - International Journal of …, 2022 - mdpi.com
Epigenetic modifications are known to regulate cell phenotype during cancer progression,
including breast cancer. Unlike genetic alterations, changes in the epigenome are …