Fungi are primitive eukaryotes and have adapted to a variety of niches during evolution.
Some fungal species may interact with other life forms (plants, insects, mammals), but are …

Much progress has been made in the last decade in identifying genes responsible for
antifungal resistance in Candida albicans. Attention has focused on five major C. albicans …

The ABC transporter genes CDR1 and CDR2 can be upregulated in Candida albicans
develo** resistance to azoles or can be upregulated by exposing cells transiently to drugs …

TAC1, a Candida albicans transcription factor situated near the mating-type locus on
chromosome 5, is necessary for the upregulation of the ABC-transporter genes CDR1 and …

Infections by opportunistic pathogenic fungi, especially Candida species, Cryptococcus
neoformans, and Aspergillus fumigatus, are a serious medical problem in …

In the light of multidrug resistance (MDR) among pathogenic microbes and cancer cells,
membrane transporters have gained profound clinical significance. Chemotherapeutic …

Candida albicans is the most common etiological agent of vaginal candidiasis. Elevated
host estrogen levels and the incidence of vaginal candidiasis are positively associated …

Azole resistance in Candida albicans can be mediated by the upregulation of the ATP
binding cassette transporter genes CDR1 and CDR2. Both genes are regulated by a cis …

Invasive fungal infections cause significant morbidity and mortality in immunocompromised
patients. Azoles, and fluconazole in particular, are very active against Candida albicans, and …

As a frequently occurring infectious disease mainly caused by Candida albicans,
vulvovaginal candidosis (VVC) affects more than 100 million women worldwide every year …