Current data suggest that infection with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) causing corona virus disease-19 (COVID-19) seems to follow a more severe …

Vitamin D and cholesterol metabolism overlap significantly in the pathways that contribute to
their biosynthesis. However, our understanding of their independent and co-regulation is …

Abstract Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of
cardiovascular disease, which is associated with poor outcomes from coronavirus infections …

Abstract Background Randomized controlled trials (RCTs) of lipid-lowering therapy (LLT) in
which the control groups received placebo without background LLT offer unique insights into …

Atherosclerosis is a multifactorial vascular disease that leads to inflammation and stiffening
of the arteries and decreases their elasticity due to the accumulation of calcium, small dense …

Objective: We aimed to evaluate alirocumab-and evolocumab-related adverse events (AEs)
in real-world compared with all other drugs, overall and by gender and age subgroups; we …

Phyto-coumarins demonstrate diverse biological actions, encompassing antiradical, anti-
inflammatory, oncolytic, monoamine oxidase B (MAOB) suppression, and antibacterial …

Statins are the most prescribed and effective drugs to treat cardiovascular diseases (CVD).
Nevertheless, these drugs can be responsible for skeletal muscle toxicity which leads to …

Fucoidan is a marine polysaccharide. In recent years, fucoidan has attracted wide-scale
attention from the pharmaceutical industries due to its diverse biological activities such as …

Statins inhibit HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, and
are the cornerstone of lipid-lowering treatment. They significantly reduce cardiovascular …