The diagnosis and treatment of age-related macular degeneration

A Stahl - Deutsches Ärzteblatt International, 2020 - pmc.ncbi.nlm.nih.gov
Background Age-related macular degeneration (AMD) is thought to cause approximately 9%
of all cases of blindness worldwide. In Germany, half of all cases of blindness and high …

[HTML][HTML] Real-world outcomes in patients with neovascular age-related macular degeneration treated with intravitreal vascular endothelial growth factor inhibitors

H Mehta, A Tufail, V Daien, AY Lee, V Nguyen… - Progress in retinal and …, 2018 - Elsevier
Clinical trials identified intravitreal vascular endothelial growth factor inhibitors (anti-VEGF
agents) have the potential to stabilise or even improve visual acuity outcomes in …

[HTML][HTML] Quantitative analysis of OCT for neovascular age-related macular degeneration using deep learning

G Moraes, DJ Fu, M Wilson, H Khalid, SK Wagner… - Ophthalmology, 2021 - Elsevier
Purpose To apply a deep learning algorithm for automated, objective, and comprehensive
quantification of optical coherence tomography (OCT) scans to a large real-world dataset of …

Impact of macular fluid volume fluctuations on visual acuity during anti-VEGF therapy in eyes with nAMD

U Chakravarthy, M Havilio, A Syntosi, N Pillai, E Wilkes… - Eye, 2021 - nature.com
Objectives To study the effect of repeated retinal thickness fluctuations during the anti-VEGF
therapy maintenance phase in neovascular age-related macular degeneration (nAMD) …

Ranibizumab treatment in treatment-naive neovascular age-related macular degeneration: results from LUMINOUS, a global real-world study

FG Holz, MS Figueroa, F Bandello, Y Yang, M Ohji… - Retina, 2020 - journals.lww.com
Purpose: To evaluate the effectiveness, safety, and treatment patterns of ranibizumab 0.5 mg
in treatment-naive patients with neovascular age-related macular degeneration enrolled in …

Impact of COVID-19 on outpatient visits and intravitreal treatments in a referral retina unit: let's be ready for a plausible “rebound effect”

E Borrelli, D Grosso, G Vella, R Sacconi… - Graefe's Archive for …, 2020 - Springer
Purpose To quantify the shrinking in outpatient and intravitreal injections' volumes in a
tertiary referral retina unit secondary to virus causing coronavirus disease 2019 (COVID-19) …

[HTML][HTML] SIERRA-AMD: a retrospective, real-world evidence study of patients with neovascular age-related macular degeneration in the United States

AM Khanani, A Skelly, V Bezlyak, R Griner… - Ophthalmology …, 2020 - Elsevier
Purpose Characterize real-world baseline visual acuity (VA) and anti-vascular endothelial
growth factor (VEGF) treatment patterns in neovascular age-related macular degeneration …

Short-term outcomes of patients with neovascular exudative AMD: the effect of COVID-19 pandemic

E Borrelli, D Grosso, G Vella, R Sacconi… - Graefe's Archive for …, 2020 - Springer
Purpose To estimate the impact of delayed care during the coronavirus disease 2019
(COVID-19) pandemic on the outcomes of patients with neovascular age-related macular …

Systematic review: non-adherence and non-persistence in intravitreal treatment

C Ehlken, F Ziemssen, N Eter, I Lanzl… - Graefe's Archive for …, 2020 - Springer
Purpose Intravitreal injection of VEGF inhibitors has become the standard of care for
different macular diseases within the last years resulting in improved visual outcomes …

Ten-year outcomes of antivascular endothelial growth factor therapy in neovascular age-related macular degeneration

S Chandra, C Arpa, D Menon, H Khalid, R Hamilton… - Eye, 2020 - nature.com
Purpose Single center, noninterventional cohort study to assess 10-year visual and
anatomical outcomes following initiation of treatment with antivascular endothelial growth …