Behçet syndrome is a rare, chronic inflammatory disease of unknown aetiopathogenesis,
most commonly presenting with mucocutaneous and ocular manifestations. Vascular …

Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …

Abstract The interleukin (IL)-1 family member IL-1α is a ubiquitous and pivotal pro-
inflammatory cytokine. The IL-1α precursor is constitutively present in nearly all cell types in …

At present infertility is affecting about 15% of couples and male factor is responsible for
almost 50% of infertility cases. Oxidative stress, due to enhanced Reactive Oxygen Species …

The presence of symptom clusters, regional differences in disease expression and
similarities with, for example, Crohn's disease suggest multiple pathological pathways are …

Behcet's disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology
characterized by recurrent episodes of oral aphthous ulcers, genital ulcers, skin lesions …

Behçet's disease (BD) is a chronic vasculitis characterized by systemic immune aberrations.
However, a comprehensive understanding of immune disturbances in BD and how they …

Behçet's disease (BD) is a systemic inflammatory disease with a chronic, relapsing-remitting
course of unknown etiology hallmarked predominantly by mucocutaneous lesions and …

Thrombosis is a common disorder with a relevant burden of morbidity and mortality
worldwide, particularly among elderly patients. Growing evidence demonstrated a direct role …

Inflammatory diseases involve numerous disorders and medical conditions defined by an
insufficient level of self-tolerance. These diseases evolve over the course of a multi-step …