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Incipient and subclinical tuberculosis: a clinical review of early stages and progression of infection
Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a
limited understanding of its clinical pathogenic spectrum of infection and disease …
limited understanding of its clinical pathogenic spectrum of infection and disease …
The natural history of untreated pulmonary tuberculosis in adults: a systematic review and meta-analysis
Stages of tuberculosis disease can be delineated by radiology, microbiology, and
symptoms, but transitions between these stages remain unclear. In a systematic review and …
symptoms, but transitions between these stages remain unclear. In a systematic review and …
Latent tuberculosis: two centuries of confusion
The current dogma is that 2 billion individuals, making up a quarter of the world's population,
are latently infected with Mycobacterium tuberculosis (1–4). It is thought that latent …
are latently infected with Mycobacterium tuberculosis (1–4). It is thought that latent …
The ongoing challenge of latent tuberculosis
The global health community has set itself the task of eliminating tuberculosis (TB) as a
public health problem by 2050. Although progress has been made in global TB control, the …
public health problem by 2050. Although progress has been made in global TB control, the …
HIV infection and multidrug resistant tuberculosis: a systematic review and meta-analysis
Background Multidrug-resistant tuberculosis (MDR-TB) in HIV infected individuals is a
serious threat to global efforts to combat tuberculosis. Inconsistent findings on the …
serious threat to global efforts to combat tuberculosis. Inconsistent findings on the …
Tuberculosis screening among ambulatory people living with HIV: a systematic review and individual participant data meta-analysis
Background The WHO-recommended tuberculosis screening and diagnostic algorithm in
ambulatory people living with HIV is a four-symptom screen (known as the WHO …
ambulatory people living with HIV is a four-symptom screen (known as the WHO …
Scaling up interventions to achieve global tuberculosis control: progress and new developments
Tuberculosis is still one of the most important causes of death worldwide. The 2010 Lancet
tuberculosis series provided a comprehensive overview of global control efforts and …
tuberculosis series provided a comprehensive overview of global control efforts and …
Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography
Tuberculosis is classically divided into states of latent infection and active disease. Using
combined positron emission and computed tomography in 35 asymptomatic, antiretroviral …
combined positron emission and computed tomography in 35 asymptomatic, antiretroviral …
Latent tuberculosis infection–revisiting and revising concepts
Host-and pathogen-specific factors interplay with the environment in a complex fashion to
determine the outcome of infection with Mycobacterium tuberculosis (Mtb), resulting in one …
determine the outcome of infection with Mycobacterium tuberculosis (Mtb), resulting in one …
Tuberculosis IRIS: pathogenesis, presentation, and management across the spectrum of disease
Antiretroviral therapy (ART), while essential in combatting tuberculosis (TB) and HIV
coinfection, is often complicated by the TB-associated immune reconstitution inflammatory …
coinfection, is often complicated by the TB-associated immune reconstitution inflammatory …