Improvements in understanding the neurobiological basis of mental illness have
unfortunately not translated into major advances in treatment. At this point, it is clear that …

Our capacity to measure diverse aspects of human biology has developed rapidly in the past
decades, but the rate at which these techniques have generated insights into the biological …

Gambling Disorder is a prevalent psychiatric condition often linked to dysfunction of
cognitive domains regulating impulsive behavior. Despite the centrality of impulsivity to …

The substantial individual heterogeneity that characterizes people with mental illness is
often ignored by classical case–control research, which relies on group mean comparisons …

Highlights•Resting-state fMRI biomarkers in psychiatry often lack disorder specificity.•
Transdiagnostic study designs allow direct assessment of biomarker specificity.•p-factor …

Psychopathology is rooted in neurodevelopment. However, clinical and biological
heterogeneity, together with a focus on case-control approaches, have made it difficult to link …

Background: Promising models for cognitive rehabilitation in alcohol treatment rest on a
more nuanced understanding of the associated impairments in the multifaceted domains of …

Introduction Impulsivity and compulsivity are important constructs, relevant to understanding
behaviour in the general population, as well as in particular mental disorders (eg attention …

Cortical variations in cytoarchitecture form a sensory-fugal axis that shapes regional profiles
of extrinsic connectivity and is thought to guide signal propagation and integration across …

Obsessive-compulsive disorder (OCD) and pathological gambling (PG) are accompanied by
deficits in behavioural flexibility. In reinforcement learning, this inflexibility can reflect …