Quality of life in Parkinson's disease: A systematic review and meta‐analysis of comparative studies

N Zhao, Y Yang, L Zhang, Q Zhang… - CNS neuroscience & …, 2021 - Wiley Online Library
Background Studies regarding the impact of Parkinson's disease (PD) on quality of life
(QOL) have reported conflicting results, and the underlying QOL domains require further …

Progression of grey and white matter brain damage in Parkinson's disease: a critical review of structural MRI literature

E Sarasso, F Agosta, N Piramide, M Filippi - Journal of neurology, 2021 - Springer
The current review summarizes the current knowledge on longitudinal cortical and
subcortical grey and white matter MRI findings assessed using T1-weighted and one-tensor …

Two distinct trajectories of clinical and neurodegeneration events in Parkinson's disease

C Zhou, L Wang, W Cheng, JC Lv, X Guan… - npj Parkinson's …, 2023 - nature.com
Increasing evidence suggests that Parkinson's disease (PD) exhibits disparate spatial and
temporal patterns of progression. Here we used a machine-learning technique—Subtype …

Enhancing early Parkinson's disease detection through multimodal deep learning and explainable AI: insights from the PPMI database

V Dentamaro, D Impedovo, L Musti, G Pirlo… - Scientific Reports, 2024 - nature.com
Parkinson's is the second most common neurodegenerative disease, affecting nearly 8.5 M
people and steadily increasing. In this research, Multimodal Deep Learning is investigated …

Tracking cortical changes throughout cognitive decline in Parkinson's disease

M Filippi, E Canu, G Donzuso, T Stojkovic… - Movement …, 2020 - Wiley Online Library
Background The objectives of this study were to investigate progressive cortical thinning and
volume loss in Parkinson's disease (PD) patients with different longitudinal patterns of …

Morphological basis of Parkinson disease-associated cognitive impairment: an update

KA Jellinger - Journal of Neural Transmission, 2022 - Springer
Cognitive impairment is one of the most salient non-motor symptoms of Parkinson disease
(PD) that poses a significant burden on the patients and carers as well as being a risk factor …

[HTML][HTML] Progressive brain atrophy and clinical evolution in Parkinson's disease

M Filippi, E Sarasso, N Piramide, T Stojkovic… - NeuroImage: Clinical, 2020 - Elsevier
Clinical manifestations and evolution are very heterogeneous among individuals with
Parkinson's disease (PD). The aims of this study were to investigate the pattern of …

The structural changes of gray matter in Parkinson disease patients with mild cognitive impairments

L Li, B Ji, T Zhao, X Cui, J Chen, Z Wang - Plos one, 2022 - journals.plos.org
Objectives Parkinson disease (PD) is associated with cognitive impairments. However, the
underlying neural mechanism of cognitive impairments in PD is still not clear. This study …

[HTML][HTML] Pathobiology of cognitive impairment in Parkinson disease: challenges and outlooks

KA Jellinger - International Journal of Molecular Sciences, 2023 - mdpi.com
Cognitive impairment (CI) is a characteristic non-motor feature of Parkinson disease (PD)
that poses a severe burden on the patients and caregivers, yet relatively little is known about …

Mild cognitive impairment in Parkinson's disease: current view

KA Jellinger - Frontiers in Cognition, 2024 - frontiersin.org
Parkinson's disease (PD), the most common motor movement disorder and second most
common neurodegenerative disorder after Alzheimer's disease (AD), is often preceded by a …